At a recent meeting in London, of the Royal Miscroscopical Society, Dr. Dallinger gave his annual address to what was probably the largest gathering of Fellows ever assembled on a similar occasion. After briefly referring to the increased interest lately manifested in the study of minute organisms, and recalling the characteristics of the doctrines of abiogenesis and biogenesis, he passed rapidly in review the results of the observations of Tyndall, Huxley, and Pasteur as bearing upon these questions, and called attention to the observations of Buchner as to the transformation of _Bacillus anthracis_ and _Bacillus subtilis_, and _vice versa_, and referred with approval to Dr. Klein's criticisms thereon. Having spoken of the desirability of careful and continuous study of this class of organisms, and the importance of endeavoring to establish the relation of the pathogenic form to the whole group, he said he should be better able to deal with the subject by recording a few ascertained facts rather than by making a more extended review, and he therefore devoted the main part of his address to a description of "the life history of a septic organism hitherto unknown to science." In his observations of this form--extending over four years--he had the advantage of the highest quality of homogeneous lenses obtainable, ranging from one-tenth to one-fiftieth of an inch, his chief reliance being placed upon a very perfect one thirty-fifth of an inch; and from the continuous nature of the observations as well as the circumstances under which they were carried on, dry lenses had for the most part to be employed. Having in his possession a maceration of cod-fish in a fluid obtained from boiled rabbits, he found at the bottom of it, when in an almost exhausted condition, a precipitate forming a slightly viscid mass, to which his attention was particularly directed. It was seen to contain a vast number of _Bacterium termo_, but on examination with a one-tenth inch objective showed that it also contained a comparatively small number of intensely active organisms--one being discovered in about eight or ten drops of the sediment. These measured 1-10,000 of an inch in length by 1-19,500 of an inch in breadth. The fluid had originally been kept at a temperature of 90° to 95° F., and it was noticed that, when placed upon a cold stage under the microscope, the movements of the organisms became, gradually slower, until at last they entirely ceased; the necessity, therefore, arose for the use of a warm stage, and the very ingenious contrivance by which a continuous and even temperature was maintained within the one-tenth of a degree was exhibited. The greatest difficulty in the matter was, however, experienced in obtaining specimens for observation, in order to be able to trace them from their earliest to their latest stage. The President then explained, by means of an admirable series of illustrations projected upon a screen by the oxyhydrogen lantern, the