The only three substances that actually checked and destroyed its vitality were phenic acid (5 per cent.), camphor (20 per cent.), olive oil (25 per cent.), in combination. For the last I substitute glycerine, because this allows the mixture to penetrate farther into the mucous membrane than oil, the latter favoring a tendency to pass over the surface. This mixture when heated separates into two layers, the upper one viscid and forming a sort of "glycerol," the lower clear. The latter will completely sterilize a thread dipped in a pure culture of the diphtheria bacillus. Corrosive sublimate was not examined because in strong enough doses it would be dangerous and in weaker ones it would be useless. The facts obtained in regards to the streptococcus of erysipelas are reported as follows: That both chemical and experimental evidence teach the extreme ease of a renewed attack of the disease; that it is possible to kill guinea pigs by an intoxication when they are immune to an inoculation of the culture in ordinary quantities. And this latter fact should warn experimenters trying to obtain immunity in man by the inoculation of non-pathogenic bacteria, because the same results may be reached. A new theory in regard to fevers and the relation of micro-organisms is suggested by Roussy, viz.: That it is a fermentation produced by a diastase or soluble ferment found in all micro-organisms and cells, and which they use in attacking and transforming matter, either inside their substance or without it. The resemblance of the malaria parasite to that of recurrent fever is noted in the work of Sacharoff. He states that there exists in the blood of those suffering from recurrent fever a hæmatozoon, which is most prominent after the fever has begun to fall, when it is of enormous proportions, twenty or more diameters of a red blood corpuscle, although smaller ones may still be found. The parasite consists of a delicate amoeboid body containing a multitude of dark, round, uniform, sharply outlined, movable granules. Besides these, the protoplasm contains a generally grayish homogeneous nucleus as large as one or two red blood corpuscles. The protoplasm sends out pseudopodia (with granules), which sometimes separate and appear as small delicate pieces of protoplasm. They vary in size, and are often swallowed by the red blood corpuscles in which they grow, and finally develop into the above mentioned amoeboid bodies.