When the urea is stationary, which is most frequently the case, it is necessary to calculate the coefficient of oxidation; that is, the relation existing between the solid matters of the urine and the urea. The elevation of the coefficient is _prima facie_ evidence the obesity is due to excess of assimilation, while depression of the coefficient indicates default of assimilation. In the first case, water and liquids must be denied as far as possible, the same as if there was no augmentation of urea; in the second, the same as if there was diminution of urea, the patients may be permitted to imbibe fluids at pleasure. For the obese from default of disassimilation, Robin recommends a regimen of green vegetables and bread chiefly--the latter in small quantities, however, and fluids as may be desired. By this means, on one occasion, he was able in the course of one month to diminish the weight of a female patient by twelve and a half pounds, her measurement around the waist at the same time decreasing 5.2 inches and across the stomach 4.8 inches. M. De St. Germain achieved good results by combining judicious exercise with moderate alimentation, excluding wine and bread. M. Dujardin Beaumetz, who professes to have given most close and careful study and attention to regimen for the obese, outlines the following, provided there is no evidence of fatty degeneration of heart. _Breakfast_ (at 8 a. m.)--Three-fourths of an ounce of bread "_en flute_"--that is abounding with crust; one and a half ounces of cold meat, ham or beef, six ounces weak black tea, _sans_ sugar. _Lunch_ (at 1 p.m.)--An ounce and a half to two ounces of bread, or a _ragout_, or two eggs; three ounces green vegetables; one-half ounce of cheese; fruits at discretion. _Dinner_ (at 7 p.m.)--An ounce and a half to two ounces of bread; three to four ounces of meat, or _ragout_; ditto of green vegetables, salad, half an ounce of cheese, fruit _ad libitum_. At meal times the patient may take only a "glass and a half" of liquid--approximately ten ounces--though a greater amount may be permitted if he abstains during the intervals.