15. Temperature, pulse, and respiration in scurvy 186 16. Subperiosteal hemorrhage and separation of epiphysis. Roentgenogram 192 17. Periosteal "tags" and "streamers." Roentgenogram 193 18. Infant with marked scurvy. Characteristic position 198 19. Scorbutic beading of ribs. Roentgenogram 198 20. "White line." Roentgenogram 199 21. Cardiac enlargement. Roentgenogram 200 22. Electrocardiogram showing "cardiorespiratory syndrome" 201 23. Stationary weight during cure of scurvy. Oliguria followed by polyuria 206 24. Development of scurvy in spite of normal gain in weight 214 25. Retardation of growth in length when no orange juice was given and supergrowth when given once more 216 TABLES TABLE PAGE 1. Fecal flora of scorbutic infants 29 2. Necropsy reports of scurvy 82 3. Relative distribution of the antiscorbutic factor in the commoner foodstuffs 157 4. Platelets and other blood cells in scurvy 209 5. Data of epidemic of scurvy 218 6. Duration of treatment before marked improvement was noticed 237 SCURVY PAST AND PRESENT CHAPTER I HISTORY OF SCURVY[1] [1] The best historical review of scurvy is to be found in Hirsch's Handbook of Geographic and Historical Pathology, from which account we have drawn many facts. =Outbreaks on Land.=--Like many other diseases, the life history of scurvy shows several distinct phases. We hear of it first as a plague, infesting armies and besieged towns; then as a dread disease, decimating the sailors of the navy and of the mercantile marine, and, since the end of the last century, more often as a nutritional disturbance, endangering the health of infants. Very recently it has acquired an entirely new interest, as the representative of a class of disorders which has revealed the essential importance to man of unknown dietary factors.