The directions for use were: Give one powder three times a day, before meals, dissolved in half a tea-cup of Hot Coffee, Tea, Whisky, Milk, Gin, &c. Use either the brown or white powder, as the colour of the liquid may require. The powders had an average weight of 4·2 grains, single powders varying from 2·9 to 6·0 grains. The composition of both kinds was found to be the same except for the trace of colouring matter contained in the tinted powder. Analysis showed the composition to be— Acetanilide 6 parts. Potassium bromide 35 ” Sugar of milk 59 ” The estimated cost of the ingredients for 50 powders was one-third of a penny. ANTIDIPSO. This is supplied by another “Chemical Company,” giving an address in London. The price of a box, containing 48 powders, 24 being white, and 24 tinted pinkish-buff, was 10s. The statements made about this article, in circulars and letters, were very similar to those made about the preceding one. A few extracts will suffice: You will not forget that to insure an absolute complete and permanent cure for the craving, two boxes are invariably required. We have had data of cures effected with one box, but to make absolutely sure you will do well to immediately send us remittance, to the same value as the last, and get the second box of the specific. Antidipso may be administered with or without the knowledge of the patient.... We enclose you a booklet showing our agency terms. Kindly give it your attention, as we are confident you will be so surprised and satisfied at the cure which will be effected that you will either yourself want to take up agency with us, or get some one in your district to do so. The directions were: Give one powder, dissolved in half a tea-cup of hot coffee, whisky, milk, gin, &c. (using either Brown or White Powder as colour of liquid may require) 3 times a day before meals. The powders had an average weight of 5·3 grains, single powders ranging from 3·7 to 9·9 grains. The white and tinted powders were made of the same constituents, with a trace of colouring matter added in the latter case, but in different proportions. Analysis showed the composition to be: WHITE POWDERS. Potassium bromide 24·5 parts. Sugar of milk 75·5 ” COLOURED POWDERS. Potassium bromide 35 parts. Sugar of milk 65 ” The estimated cost of the ingredients for 48 powders was one-third of a penny. THE TEETOLIA TREATMENT. The following is an extract from an advertisement of a “Teetolia Treatment Association,” giving an address in London: After years of Drink and Drug taking— Cured in 4 days.