Intra-Venous Injection, after thorough tests under the most favourable conditions, proved absolutely ineffective. Trachael (_sic_) Injection has also been tried with equally unsatisfactory results. Inoculation with lymph from tuberculous animals not only utterly failed, but frequently hastened the patient’s death. Antimony, prussic acid, emetics, blisters, mercury, iron, digitalis, clover, and numerous other drugs, have all proved useless, for they failed to have any action upon the cause of the disease, and only gave the patient temporary relief, if they produced any beneficial effects at all. In treating consumption in the past, physicians making Tuberculosis a speciality have been accustomed to recommend creosote and its product guaiacol, while later arsenic has found a certain amount of favour. These physicians have undoubtedly been honest and conscientious in prescribing such treatment, for they were upheld by the practice of years, and the indorsement of the greatest specialists in each generation for a hundred years. Yet they were wrong; just as wrong and just as ignorant of the true remedy for consumption as the ancients were of geography before the new world was discovered. Against the use of creosote or guaiacol, Dr. Yonkerman speaks positively and emphatically, and his opinions have now the support of all present-day physicians making Tuberculosis their special study. A “Life History of Dr. Derk P. Yonkerman” was also given, from which it appeared that the home of Tuberculozyne is in Michigan, U.S.A. The book was accompanied by a long letter, and this was followed at intervals by others; these were all printed to appear as typewritten, and dealt chiefly with the terrors of consumption if neglected, the importance of taking Tuberculozyne at once, and, after a supply had been sent, with the necessity of continuing its use even if no apparent benefit results. A few extracts are here given: You need not be discouraged or believe your case incurable, even if you have tried all the usual remedies and found no relief, for hundreds of our cured patients have had the same experience; after all other remedies had failed to even stop the progress of their disease, they tried Tuberculozyne and were quickly cured. From the third letter: We realize that since you were taken ill your expenses must have been burdensome, and if you feel that at the moment the cost of a complete treatment of Tuberculozyne is more than you can readily meet, we will send you the full month’s supply upon receipt of but 40s.; the remaining 10s. you may pay at your own convenience when you are fully satisfied that your cure is complete and permanent. From the fifth: