Here let me say that the staff of the Lister Institute for medical
research has done work in its laboratories in Chelsea Gardens of the
very greatest national importance during the war. It was founded by
public subscription, and has now an endowment of some £10,000 a year.
Sir David Bruce, the chairman of its Council, gives in the Report of
the Governing Body for 1919 a very striking summary of the work done
in the laboratories and by the staff of the Institute. The successful
investigation of trench fever and of tetanus, of the destruction of
lice, and of the effects of cold storage on food, besides the study
of scurvy and other diseases due to deficiency of what are now called
"_accessory food factors_," are, we learn, the chief matters in
which the Lister Institute was engaged in the year 1918-19. Besides
this, however, at its farm at Elstree it has prepared and supplied
to the War Office, the Admiralty, the Overseas Forces, and the Local
Government Board more than a million doses of anti-toxins (diphtheria
and tetanus), bacterial vaccines (cholera, plague, influenza), and
other similar curative fluids–requiring for their safe production the
highest skill and most complete knowledge of recent discovery. And this
is only a sample of what the Lister Institute has been doing for many
consecutive years.
Now we return to the investigation of scurvy. Within the last ten
years the fact has been established (which was more or less guessed
and acted upon by medical men of past days) that, in order to
maintain health, the diet of man and of many animals must contain
not merely the necessary quantities of meat or cheese-like bodies,
of fat and starch and sugar, but also minute quantities of accessory
food-factors which it is convenient to term "vitamines." The name
serves (though its etymology is unsatisfactory) to indicate certain
"proteids" or highly complex nitrogenous compounds which are only to
be obtained from fresh and uncooked or slightly heated vegetables
and from some foods of animal origin. These "vitamines" are destroyed
by heat and by desiccation. They have not yet been isolated though
in some cases extracted in a nearly pure state. Their presence or
absence is demonstrated by careful experiments in feeding animals,
such as guinea-pigs, with weighed quantities of different foods.
The "vitamine" is often found to be present only in one part of a
seed or fruit or special kind of fat liable to be rejected in food
preparation. An important fact is that it may not amount to as much as
one-ten-thousandth of the weight of the food in which it occurs; and
the part containing it may be overlooked and rejected, or its value
destroyed by heat or by desiccation. A committee on these "accessory
food-factors" is carrying on experiments at the Lister Institute. Dr.
F. G. Hopkins, F.R.S., who first discovered the importance of one of
these factors in feeding young rats, is the chairman, and Dr. Harriette
Chick is the secretary.
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