In September and October, 1899, 63 cases of typhoid fever, resulting in 5 deaths, occurred at the Northampton (Mass.) insane hospital. This epidemic was conclusively traced to celery, which was eaten freely in August and was grown and banked in a plot that had been fertilized in the late winter or early spring with the solid residue and scrapings from a sewage filter bed situated on the hospital grounds. Some years ago Dr. W. W. Skinner, Bureau of Chemistry, Department of Agriculture, investigated the cause of an outbreak of typhoid fever in southwest Virginia. A small stream meandered through a narrow valley in which five 10-inch wells about 450 feet deep had been drilled in limestone formation. The wells were from 50 to 400 feet from the stream, from which, it was suspected, pollution was reaching the wells. In a pool in the stream bed approximately one-fourth mile above the wells several hundred pounds of common salt were dissolved. Four of the wells were cut off from the pump and the fifth was subjected to heavy pumping. The water discharged by the pump was examined at 15-minute intervals and its salt content determined over a considerable period of time. After the lapse of several 15-minute intervals the salt began to rise and continued to rise until the maximum was approximately seven times that at the beginning of the test, thus proving the facility with which pollution may pass a long distance underground and reach deep wells. Probably no epidemic in American history better illustrates the dire results that may follow one thoughtless act than the outbreak of typhoid fever at Plymouth, Pa., in 1885. In January and February of that year the night discharges of one typhoid fever patient were thrown out upon the snow near his home. These, carried by spring thaws into the public water supply, caused an epidemic running from April to September. In a total population of about 8,000, 1,104 persons were attacked by the disease and 114 died. Like plants and animals, disease germs vary in their powers of resistance. Some are hardy, others succumb easily. Outside the body most of them probably die in a few days or weeks. It is never certain when such germs may not lodge where the immediate surroundings are favorable to their life and reproduction. Milk is one of the common substances in which germs multiply rapidly. The experience at Northampton shows that typhoid-fever germs may survive several months in garden soil. Laboratory tests by the United States Public Health Service showed that typhoid-fever germs had not all succumbed after being frozen in cream 74 days. (Public Health Reports, Feb. 8, 1918, pp. 163-166.) Ravenel kept the spores of anthrax immersed for 244 days in the strongest tanning fluids without perceptible change in their vitality or virulence. (Annual Report, State Department of Health, Mass., 1916, p. 494.)