Miss F---- was about twenty years old when she completed her technical education. She inherited a nervous diathesis as well as a large dower of intellectual and aesthetic graces. She was a good student, and conscientiously devoted all her time, with the exception of ordinary vacations, to the labor of her education. She made herself mistress of several languages, and accomplished in many ways. The catamenial function appeared normally, and, with the exception of occasional slight attacks of menorrhagia, was normally performed during the whole period of her education. She got on without any sort of serious illness. There were few belonging to my clientele who required less professional advice for the same period than she. With the ending of her school life, when she should have been in good trim and well equipped, physically as well as intellectually, for life's work, there commenced, without obvious cause, a long period of invalidism. It would be tedious to the reader, and useless for our present purpose, to detail the history and describe the protean shapes of her sufferings. With the exception of small breasts, the reproductive system was well developed. Repeated and careful examinations failed to detect any derangement of the uterine mechanism. Her symptoms all pointed to the nervous system as the _fons et origo mali_. First general debility, that concealed but ubiquitous leader of innumerable armies of weakness and ill, laid siege to her, and captured her. Then came insomnia, that worried her nights for month after month, and made her beg for opium, alcohol, chloral, bromides, any thing that would bring sleep. Neuralgia in every conceivable form tormented her, most frequently in her back, but often, also, in her head, sometimes in her sciatic nerves, sometimes setting up a tic douloureux, sometimes causing a fearful dysmenorrhoea and frequently making her head ache for days together. At other times hysteria got hold of her, and made her fancy herself the victim of strange diseases. Mental effort of the slightest character distressed her, and she could not bear physical exercise of any amount. This condition, or rather these varying conditions, continued for some years. She followed a careful and systematic regimen, and was rewarded by a slow and gradual return of health and strength, when a sudden accident killed her, and terminated her struggle with weakness and pain.