Sex-linked Inheritance in DrosophilaMorgan, Thomas Hunt
Science
Sex-linked Inheritance in Drosophila
Morgan, Thomas Hunt
Drosophila; Heredity
In each experiment the percentage of crossing-over is found by dividing the
number of the cross-overs by the sum of the non-cross-overs and the
cross-overs, and multiplying this quotient by 100. The resulting
percentages, or cross-over values, are used as measures of the distances
between loci. Thus if the experiments give a cross-over value of 5 per cent
for white and bifid, we say that white and bifid lie 5 units apart in the X
chromosome. Other experiments show that yellow and white are about 1 unit
apart, and that yellow and bifid are about 6 units apart. We can therefore
construct a diagram with yellow as {21} the zero, with white at 1, and with
bifid at 6. If we know the cross-over values given by a new mutant with any
two mutants of the same chromosome whose positions are already determined,
then we can locate the new factor with accuracy, and be able to predict the
cross-over value which the new factor will give with any other factor whose
position is plotted.
_The sex-linked factors of Drosophila._
+------------+----------+-------+-------+--------+------------+---------+
| Gen. | Part |Figure.|Symbol.| Locus. | Date found.|Found by.|
| |affected. | | | | | |
+------------+----------+-------+-------+--------+------------+---------+
|White |Eye-color | 11 | w | 1.1 | May 1910 |Morgan. |
|Rudimentary |Wings | A | r | 55.1 | June 1910 |Morgan. |
|Miniature |Wings | 7-8 | m | 36.1 | Aug. 1910 |Morgan. |
|Vermilion |Eye-color | 10 | v | 33.0 | Nov. 1910 |Morgan. |
|Yellow |Body-color| 5 | y | 0.0 | Jan. 1911 |Wallace. |
|Abnormal |Abdomen | 4 | A' | 2.4 | July 1911 |Morgan. |
|Eosin |Eye-color | 7-8 | w^e | 1.1 | Aug. 1911 |Morgan. |
|Bifid |Wings | B | b_i | 6.3 | Nov. 1911 |Morgan. |
|Reduplicated|Legs | | | 34.7 | Nov. 1911 |Hoge. |
|Lethal 1 |Life | | l_1 | 0.7 | Feb. 1912 |Rawls. |
|Lethal 1_a_*|Life | | l_1a | 3.3 | Mar. 1912 |Rawls. |
|Spot* |Body-color| 14-17 | y^s | 0.0 | April 1912 |Cattell. |
|Sable* |Body-color| 2 | s | 43.0 | July 1912 |Bridges. |
|Dot* |Thorax | | | 33 +/- | July 1912 |Bridges.
|
|Bow* |Wings | C | | | Aug. 1912 |Bridges. |
|Lemon* |Body-color| 3 | l_m | 17.5 | Aug. 1912 |Wallace. |
|Lethal 2 |Life | | l_2 | 12.5+/- | Sept. 1912 |Morgan.
|
|Cherry |Eye-color | 9 | w^c | 1.1 | Oct. 1912 |Safir. |
|Fused* |Venation | D | f_u | 59.5 | Nov. 1912 |Bridges. |
|Forked* |Bristles | E | f | 56.5 | Nov. 1912 |Bridges. |
|Shifted* |Venation | F | s_h | 17.8 | Jan. 1913 |Bridges. |
|Lethal sa |Life | | l_sa | 23.7 | Jan.
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