_Predisposition._――The innate or uncaused condition, which is so commonly found among the young, is quite likely congenital and constitutional. There is evidently structural malformation in the neuroglia, or nerve cells proper, which predisposes the child to sexual excitement. This may not be derived from the immediate parent, but far back. In the third or fourth generation, debauchés may be found. Licentious parents commonly predispose their children to morbid sexual desires; and what evidence have we that structural changes do not exist in or about the nerve centres that preside over the sexual functions, and that such changes are not constitutional? Then, with this structural change as a predisposition, the least cause will set the sexual centers into a blaze of excitement. They who are predisposed by many generations, show upon their faces the lines of coarse breeding; that they are the offspring of debauchés; congenital degradation; not but these conditions, under favorable circumstances, may be overcome, by rigidly cultivating opposite nerve centers; but such opportunities are seldom presented, and when presented seldom embraced. Circumstances are also to be considered as having a bearing upon the sexual “ups and downs” of our human career. With a predisposing sexual cause, a downfall may occur under circumstances less seductive in character than when no such congenital condition is present. Listen to the heart-rending stories of girls in the houses of prostitution. Each has her story of circumstantial events to relate. Circumstances of varied gravity have caused the multitudes of “fallen women” to occupy their degraded sphere of shame and debauch. Many of these have never been predisposed to a sexual livelihood by an erotic disposition, and they only stay by compulsion and fear of reproach that must follow if they return to society. The line of social demarkation is drawn, and there is no palliation or chance of redemption by reform――only secret forgiveness, secret repentance, or a nunnery. There are some who follow this life by choice, from the pleasure therein. Such are predisposed: they naturally follow this course: they learn it on the streets, in mere childhood: their ancestors, or some one of them at least, were of this type――mal-constructed――and circumstances are meagre that, as is said, lead them astray. They are not led astray: it is more natural to them than to pursue the path of rectitude and virtue. These people are predisposed to evil, and it is only, even if guarded from childhood up by constant watching and being kept from every possible circumstance, and taught only the good and pure, to adult life, that any reasonable assurance may be had of their safety from vice. This inheritance is almost indestructible and may crop out after the best of culture, with very slight cause, any time in adult life or in future generations.