_Masturbation_, after the age of maturity is no more injurious, aside from the degradation it leads to, than the same number of contacts in the natural manner; but in the youth the undeveloped organs suffer, as well as the nerve-centers which supply these organs with nervous energy. The youth is inclined to indulge the habit after once initiated, greatly to the detriment of the spinal cord, and through this to the general nervous system. He is inclined to practice the deplorable vice oftener than he could find opportunity to gratify his passion in the natural way. As a rule, to the indiscretions of youth is confined the permanent injury to the nervous system. It is at an early age, when so much injury is done, that the very common practice occurs at schools, when boys club together in squads and go behind embankments of stone-wall, or creek-banks; or a boy isolates himself, as it were, to “shell out a grist by hand.” With such ample opportunities, and with the habit fully established, the acts are repeated with such frequency that exhaustion of the nervous power must often attend this wonderful deviation from nature’s designs. With all this supposed nervous weakness, I do not incline to the opinion that more injury is done to the sexual organs by this practice, in and of itself, than is accomplished through the impressions wrought upon the brain from reading spermatorrhœa literature of advertising, “private-disease” specialists. I am satisfied that I have seen bad cases recover by putting their minds at ease. The carefully worded little books, that are sent broadcast to drive in those who have been indiscreet, are money-making dodges, and are of great injury to the confiding and simple. When the injury has become very extensive and the condition of habit very depraved, a young man becomes so attached to his lothly vice that he will refuse the natural way of gratifying the erotic desire. He is not in the least influenced by one of the opposite sex, and prefers his own company, or isolation. It is not the mule only that suffers from masturbation, but girls as well, though not so commonly, suffer from this peculiar sexual neurasthenia and hysteria growing out of sexual abuse. Our opportunities for discovering the extent of such practices in the unmarried female are very limited; consequently, we remain in ignorance to a great degree. The married woman furnishes the physician the majority of the practice in this class of cases, as she also suffers from a mismanagement of the sexual congress; and it is only to the married woman that the practical physician will need to devote extensive attention, and only through her, in this sphere, can much information be obtained.