The ship was soon boarded by a messenger from Mr. Wetter, the outgoing American Consul at Madagascar, and I was piloted ashore. The view of Tamatave from the ship was not prepossessing, and my walk through the city to the hotel was not inspiring. The attempt to dignify the six or eight feet wide alleys (which were the main arteries for travel) as avenues or streets, seemed ludicrous, and the filthy condition, the absence of all sanitary regulations in a province pretending a civilized administration, was to me a revelation. The natural sequence of such neglect was the visitation of the "Bubonic plague" a few months after my arrival and an immense death-rate. The alarm proved a conservator for the living, for the burning of the effected districts, widening the streets and enforcement of sanitary rules have tended to lessen its virulence, although it has been yearly in its visitations; for while foul surroundings are recognized as hot-beds for the propagation of the germs of this pest, recent experience has demonstrated that while cleanliness and rigid sanitary measures are less inviting, they are not positive barriers to its approach and dire effect. The "terror" originally supposed to be indigenous only to India, Egypt, and China, and so domestic in its habits as to confine its ravages to few precincts, now stalks forth as on a world mission--to Mauritius in Indian Ocean, to Japan, Brazil, Australia, Honolulu, and last and not least, interesting from an American point of view, are the stealthy footsteps of the unwelcome guest in the city of San Francisco, Cal. "While medical information relating to the plague is still less definite and extensive than it should be," says an eminent physician, "it is now well demonstrated that the disease depends upon a specific microbe." It may be communicated from one person to another through expectoration, oozings from the mouth of dying persons, or through the excretions of the body. "The fears it inspires are well grounded, for the recoveries in a case of severe epidemics are only ten per cent. Of 126 cases reported from Manila from January 20 to March 30, 1900, 112 cases resulted fatally." In India, where the plague has been the most severe, the deaths from this cause have averaged 5,000 a week of recent years, a considerable amount of study has been devoted to the various phases of the plague, by physicians in Europe and the East especially, and a number have given their lives to the cause of medical science in attempts to find some method of successfully combating it. It is needless to say that no specific has as yet been discovered in its treatment, and ordinary curative measures have but little effect on its course. In Chinatown, San Francisco, where it made its appearance, a rigid "cordon sanitaire" was established, and all outer intercourse prohibited. It is not believed that conditions are inviting in North America, although "the wish may be father to the thought."