Significant Achievements in Space Bioscience 1958-1964United States. National Aeronautics and Space Administration
Science
Significant Achievements in Space Bioscience 1958-1964
United States. National Aeronautics and Space Administration
Biology; Space flight
A large range of N, O, C, and H compositions are being investigated for
interesting and plausible combinations of factors. In these calculations
an IBM 7090 computer is being used to obtain data on a very large number
of combinations of chemicals. Other chemical species will be added as
the research continues. Some results of this study give an insight into
the variety of biologically significant chemicals which might have
existed during Earth’s primitive prebiological condition or may now
exist on the surfaces and in the atmospheres of other planets (refs.
[ref.151]-[ref.153]). The general method described by White et al.
([ref.152]), minimizing the free energy of the system, was used. The
solution was approached by an iterative process, starting with an
initial guess of concentrations of the compounds. At each step, _M_+1
linear equations are solved where _M_ is the number of elements in the
system.
In addition to listing of the concentrations of all compounds included
in each problem, the results of three-element problems have been
expressed on a triangular composition diagram for convenience. A coarse
grid of 60 points is used to survey all elemental compositions, with
finer grids being used in regions of particular interest. The calculated
concentrations of the compounds at each composition are stored, and
finally a series of triangular diagrams is printed out, each showing the
concentrations of as many as four compounds at the grid points.
Figure 2 shows the results obtained in the C, H, and O systems. Organic
compounds in concentrations greater than 10⁻²⁰ mole fraction are found
everywhere except where free O₂, is present. Solid carbon theoretically
becomes stable along the lower dashed line at 500° K. However, reactions
producing it are very slow. The supersaturated region beyond the line of
potential carbon formation was also investigated. A threshold was found
where polynuclear aromatic compounds are sufficiently concentrated to
form a liquid phase. These conditions may have been involved in the
primordial formation of asphaltic petroleum.
[Illustration: Figure 2.—_Equilibrium diagram for the system C-H-O._]
Jukes and associates ([ref.154]) at the University of California at
Berkeley have been investigating the code for amino acids in protein
synthesis, the key for translating the sequence of bases in DNA into the
sequence of amino acids in proteins. The amino acid code was solely a
matter of theory until Nirenberg and Matthaei ([ref.155]) at the
National Institutes of Health carried out a crucial experiment. This
experiment bridged the last remaining gap separating theoretical
genetics and test-tube biochemistry. It now became experimentally
possible to search for codes for all 20 amino acids concerned in the
synthesis of proteins.
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