I may here mention, that, after the fire of London, the College of Physicians was rebuilt on a site in Warwick Lane, which, until the erection there of the palatial residence of Guy of Warwick, the King maker, was called Eldenesse Lane. Sir Christopher Wren was the architect of the new College, and its burnished dome gave Garth the opportunity of displaying his powers of satire thus:— “Witness a dome, majestic to the sight, And sumptuous arches bear its oval height; A golden globe, placed high, with artful skill, Seems to the distant sight—a gilded pill.” Amongst the remarkable men of Harvey’s time were Shakespeare, Bacon, Van Helmont, and Sydenham, all of whom had personal intercourse with him; of these we shall first notice Thomas Sydenham, who was born in 1624. Boerhaave called him the second Hippocrates on account of his close observation of the natural phenomena of disease, but he is too well known to us to require any detailed description either of his method, or of his general knowledge. The story of his reply to Dr. Blackmore, when asked by him what books he should read, that “Don Quixote was a very good book” has been erroneously supposed to express his contempt for learning, but the joke was a personal one. Blackmore was a poet, and Sydenham saw that the man who consulted him did not possess the stuff of which doctors are made, he therefore referred him to the most lively piece of writing then in existence, as furnishing fitter pabulum for a poet, than the dry discussions of medical subjects could afford. To describe the character of Sydenham, it would be necessary to call to our aid the highest forms of panegyric; a good and honourable man, living in harmony with his brethren, and as far as the troubled state of the country would allow, in peace with all men. He lived to see the revolution of 1688 accomplished, and his aspirations as a patriot being thus gratified, he died in the following year.