Produced by Bryan Ness, Josephine Paolucci and the Online Distributed Proofreading Team at https://www.pgdp.net. (This book was produced from scanned images of public domain material from the Google Print project.) SOME CONSTITUENTS OF THE POISON IVY PLANT (RHUS TOXICODENDRON) DISSERTATION SUBMITTED TO THE BOARD OF UNIVERSITY STUDIES OF THE JOHNS HOPKINS UNIVERSITY IN CONFORMITY WITH THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY BY WILLIAM ANDERSON SYME 1906 1906 THE SUN JOB PRINTING OFFICE BALTIMORE Transcriber's Note: Underscores around words indicates italics while an underscore and curly brackets in an equation indicates a subscript. CONTENTS. Acknowledgments 4 Literature 5 Introduction 7 Work of Khittel 11 Work of Maisch 12 Work of Pfaff 13 Experimental 14 Gallic Acid 18 Fisetin 20 Rhamnose 23 The Poison 28 Potassium Permanganate as a Remedy for Rhus Poisoning 35 Summary 37 Biography 38 ACKNOWLEDGMENTS. The author desires to avail himself of this opportunity to tender his thanks to those under whose guidance he has worked while a student at the Johns Hopkins University, namely to Professors Remsen, Morse, Jones, and Andrews, and to Doctors Acree and Tingle for instruction in lecture room and laboratory. He is especially indebted to Dr. S. F. Acree, at whose suggestion this research work was undertaken, for counsel and assistance in its prosecution. He would also thank Messrs. Parke, Davis and Co., of Detroit, Mich., for the preparation of the crude material used in this investigation, and the U. S. Department of Agriculture, Washington, D. C., for electrotypes of figures 17, 18, and 19 in Bulletin No. 20, Division of Botany. LITERATURE. Acides Gummiques, Garros (Dissertation) 1895. American Chemical Journal. American Journal of the Medical Sciences. American Journal of Pharmacy. Annalen der Chemie und der Pharmacie (Liebig). Annales de Chimie et de Physique. Berichte der deutschen chemischen Gesellschaft. Biochemie der Pflanzen (Czapek) 1905. Brooklyn Medical Journal. Bulletin de la Societe Chimique. Bulletins 20 and 26 U. S. Department of Agriculture, Division of Botany. Chemie der Zuckerarten, Von Lippmann, 1904. Chemiker-Zeitung. Comptes rendus. Industries of Japan, J. J. Rein.