As Vice-President of the United States, a regent _ex-officio_ of the Smithsonian Institution, I had rare opportunity to learn much of its history and something of its marvellous accomplishment. As is well known, it bears the name of James Smithson. He was an Englishman, related to the historic family of Percy, and a lineal descendent of Henry the Seventh, his maternal ancestor being the ill-fated Lady Jane Grey, cousin to Queen Elizabeth. Mr. Langley, the late secretary of the institution, said: "Smithson always seems to have regarded the circumstances of his birth as doing him a peculiar injustice, and it was apparently this sense that he had been deprived of honors properly his which made him look for other sources of fame than those which birth had denied him, and constituted the motive of the most important action of his life, the creation of the Smithsonian Institution." The deep resentment of Smithson against the great families who had virtually disowned him, finds vent in a letter yet extant, of which the following is a part: "The best blood of England flows in my veins; on my father's side I am a Northumberland, on my mother's I am related to kings; but this avails me not. My name shall live in the memory of man when the titles of the Northumberlands and the Percys are extinct and forgotten." How truly his indignant forecast was prophetic is now a matter of history. Few men know much about the once proud families of Northumberland or Percy, but the name of the youth they scornfully disowned lives in the institution he founded, the greatest instrumentality yet devised for "the increase and diffusion of knowledge among men." Smithson was born in 1765, and received the degree of Master of Arts from Pembroke College at the age of twenty-one. A year later he was admitted a Fellow of the Royal Society, upon the recommendation of his instructors, as being "a gentleman well versed in the various branches of Natural Philosophy, and particularly in Chemistry and Mineralogy." As a student, he was devoted to the study of the sciences, especially chemistry, and his entire life, in fact, was given to scientific research. Twenty-seven papers from his pen were published in "The Philosophical Transactions of the Royal Society" and in "Thompson's Annals of Philosophy," near the close of the eighteenth and the beginning of the nineteenth century, and "all give evidence that he was an assiduous and faithful experimenter." In this connection, the statement of Professor Clarke, Chief Chemist of the United States Geographical Survey, is in point: