If, on the other hand, the discharge is very offensive and the pus more serous, watery, or bloody, there is reason to suspect the presence of some of the septic bacteria, and the results on the general system are a high fever and softening of the liver and spleen and no tendency to abscesses of the internal organs. Diarrhea is a common symptom, and death ensues early, the blood after death being found unclotted. Complicated cases are common, and in all alike the umbilical veins usually remain open and can be explored by a probe passed at first upward and then forward toward the liver. Prevention is sought by applying a lotion of carbolic acid or iodin solution to the navel string at birth, or it may be smeared with common wood tar, which is at once antiseptic and a protective covering against germs. In the absence of either a strong decoction of oak bark may be used. _Local treatment_ consists in the application of antiseptic to the surface and their injection into the vein. As a lotion carbolic acid, 1 ounce in a quart of strong decoction of oak bark, should be used, or salicylic acid or salol may be sprinkled on the surface. The interior of the vein should be swabbed out with a probe wrapped around with cotton wool and dipped in boracic salicylic acid. If complications have extended to the liver or other internal organs, or the joints, other treatment will be demanded. In acute cases of general infection an early fatal result is to be expected. PYEMIC AND SEPTICEMIC INFLAMMATION OF JOINTS IN CALVES (JOINT ILL). This occurs in young calves within the first month after birth. It persists in the joints when once attacked, and is usually connected with disease of the navel. Rheumatism, on the other hand, rarely occurs in a calf under a month old. It tends to shift from joint to joint, and is independent of any navel disease. Again, it affects the fibrous structures of the joints, and rarely results in the formation of white matter, while the affection before named attacks the structures outside as well as inside the joints and, above all, the ends of the bones, and tends to the destruction and crumbling of their tissue, and even to the formation of open sores, through which the fragile bones are exposed. The microbes from the unhealthy and infected wound in the navel pass into the system through the veins, or lymphatics, and form colonies and local inflammations and abscesses in and around the joints.