thereby lessening its volume without having the disadvantage of impoverishing the elements of the blood found in bleeding. In many cases antipyretics given by the mouth and cold applied to the skin are most useful. When the irritation which is the cause of fever is a specific one, either in the form of bacteria (living organisms), as in glanders, tuberculosis, influenza, septicemia, etc., or in the form of a foreign element, as in rheumatism, gout, hemaglobinuria, and other so-called diseases of nutrition, we employ remedies which have been found to have a direct specific action on them. Among the specific remedies for various diseases are counted quinin, carbolic acid, salicylic acid, antipyrene, mercury, iodin, the empyreumatic oils, tars, resins, aromatics, sulphur, and a host of other drugs, some of which are of known effect and others of which are theoretical in action. Certain remedies, like simple aromatic teas, vegetable acids, such as vinegar, lemon juice, etc., alkalines in the form of salts, sweet spirits of niter, etc., which are household remedies, are always useful, because they act on the excreting organs and ameliorate the effects of fever. Other remedies, which are to be used to influence the cause of fever, must be selected with judgment and from a thorough knowledge of the nature of the disease. METHODS OF ADMINISTERING MEDICINES. By CH. B. MICHENER, V. S. [Revised by Leonard Pearson, B. S., V. M. D.] Medicine may enter the body through any of the following designated channels: First, by the mouth; second, by the air passages; third, by the skin; fourth, by the tissue beneath the skin (hypodermic methods); fifth, by the rectum; sixth, by the genito-urinary passages; and, seventh, by the blood (intravenous injections). BY THE MOUTH.--Medicines can be given by the mouth in the form of solids, as powders or pills; liquids, and pastes, or electuaries. _Powders._--Solids administered as powders should be as finely pulverized as possible, in order to obtain rapid solution and absorption. Their action is in this way facilitated and intensified. Powders must be free from any irritant or caustic action upon the mouth. Those that are without any disagreeable taste or smell are readily eaten with the feed or taken in the drinking water. When placed with the feed they should first be dissolved or suspended in water and thus sprinkled on the feed. If mixed dry the horse will often leave the medicine in the bottom of his manger. Nonirritant powders may be given in capsules, as balls are given.