Studies on Epidemic Influenza: Comprising Clinical and Laboratory Investigations — John Shaqi
Studies on Epidemic Influenza: Comprising Clinical and Laboratory InvestigationsUniversity of Pittsburgh. School of Medicine
History
Studies on Epidemic Influenza: Comprising Clinical and Laboratory Investigations
University of Pittsburgh. School of Medicine
Influenza; Influenza Epidemic, 1918-1919
They probably would come more clearly under the
so-called radiation from numerous rural districts. In almost every case
at the point of its origin in these countries the epidemic developed and
spread slowly, lasting months and with very varying morbidity and
mortality. They had none of the explosive characteristics of the
pandemic. The general diminished morbidity of the later epidemic, the
diminished geographic distribution of the disease and the scarcely
recognizable character of its contagion, its slow development and
extension over several months, the continuous diminution in frequency
and in intensity since its onset in 1889, have been explained by
presumptive successive lessening of susceptibility of the population,
possibly due to acquired immunization. Observers at that time, as well
as ourselves, could question this last statement.
There was observed one noteworthy thing about seasons. While the great
pandemic of 1889 and 1890 had no definite connection with seasons, the
epidemic types which followed in 1891 and 1892 seemed to show a lighting
up in either spring or fall, remaining dormant in the summer months. It
has also been shown by the history of former epidemics that almost all
the pandemics started from Russia in the fall, winter and spring months.
Such was the case in 10 of the great pandemics of 1729 to 1889. This, no
doubt, was the reason so many of the former historical writers were
impressed by seasons and meteorological conditions. The statement made
by observers during the epidemic that influenza presented two phases,
one pandemic and the other endemic, and that each follows different
epidemiological rules, seems possible. The question raised during the
last epidemic of the spread of the disease in families, the disease
occurring at high altitudes and even at sea, we know does not interfere
with the recognition of its spread by direct contagion. Definite
examples of families or villages being infected by a returned member of
such family or citizen from abroad are reported frequently, and even the
appearance of the disease in isolated places has often been traced and
verified from a definite source, to say nothing of the question of
carriers and those supposed to be suffering from other diseases.
Striking examples are shown also in this epidemic that many
institutions, frequently those isolated from the world, were markedly
exempt until, through servants or outside visitors, the disease gained
access to them. This gave a most favorable field for the study of
invasion, spread and decline of the disease. Observations made at this
time in regard to hospitals seemed to suggest that certain institutions
were more or less exempt, although not closed institutions, while others
suffered from the first. These two types of hospital invasion are hard
to reconcile.
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