Studies on Epidemic Influenza: Comprising Clinical and Laboratory InvestigationsUniversity of Pittsburgh. School of Medicine
History
Studies on Epidemic Influenza: Comprising Clinical and Laboratory Investigations
University of Pittsburgh. School of Medicine
Influenza; Influenza Epidemic, 1918-1919
A condition which was frequently noted by the patient was an
indescribable weakness and prostration which appeared early, sometimes
before any other symptoms were noted or before any elevation of
temperature. The young soldier was in apparent perfect condition when he
arose in the early morning. During the “setting up” exercises he did not
feel so fit, and a few hours later appeared extremely weak. When his
condition was called to the attention of the medical officers he was
found to have a slight elevation of temperature and was sent to his bed.
In former epidemics, as also in this one, marked prostration was
recognized as coming at the height of the disease and remaining
persistently during convalescence. But it does not seem to be recorded
as among the first symptoms.
_Influenza with Lung Involvement_
Of the group with lung involvement much may be written from a clinical
standpoint, and much confusion may be brought about. Especially is this
so if one has no definite idea of the pathology present, or if one
enters into a discussion of the character of the infection—a point upon
which there is as yet no unanimity of opinion. From the many reports
which have been put forth from the base hospitals of the various
cantonments, and also from the reports coming from civilian practice, it
is evident that scarcely any two groups of laboratory men or any two
individuals of those separate groups have the same idea as to the
bacteriology and the pathology peculiar to this epidemic.
As long as there is this confusion and element of doubt in the minds of
those to whom we are accustomed to look, the clinician must necessarily
speak with considerable hesitancy, especially when he attempts to
interpret the physical signs observed. In our own group the observations
of Klotz, Guthrie, Holman and others have given us an interpretation of
our clinical findings which, at present at least, is more or less
satisfactory. We shall definitely keep in mind their observations and
conclusions as we go on with the description of the physical signs of
the chest in cases having lung involvement.
In the description of this group it will readily be seen that the lower
respiratory tract stood the brunt of the infection. Of the 153 soldiers
under our care, 60, or about 40 per cent., were recognized as having
pneumonia. Of these, 34 had undoubted demonstrable signs, while 26 were
questionable, and yet from the temperature and other symptoms we
concluded there was a pneumonia. Of the 394 civilians, 189, or about 50
per cent., had pneumonia. Of this group there were again some 28 or 30
in which the diagnosis was doubtful, according to the ordinary way of
making a diagnosis, but we felt sure from the temperature course that
more than a simple influenza was present. In the description of the
physical findings of the chest in these influenzas with lung involvement
it will be readily seen why the diagnosis must sometimes be in doubt.
Public-domain text, read in full here on John Shaqi.
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