They constitute no standard: so far as I have seen, the consequences show themselves only in the offspring, though in this case it must be taken into account, that the children are sometimes born before a man's health has been seriously injured. A man of exceptional strength misleads and encourages others to indulge. HYDE CLARKE. October 14, 1882. MR. WILKIE COLLINS. When I am ill (I am suffering from gout at this very moment) tobacco is the best friend that my irritable nerves possess. When I am well, but exhausted for the time by a hard day's work, tobacco nerves and composes me. There is my evidence in two words. When a man allows himself to become a glutton in the matter of smoking tobacco, he suffers for it; and if he becomes a glutton in the matter of eating meat, he just as certainly suffers in another way. When I read learned attacks on the practice of smoking, I feel indebted to the writer--he adds largely to the relish of my cigar. WILKIE COLONS. February 10, 1882. MR. MONCURE D. CONWAY, M. A. My experience of stimulants has been insufficient to enable me to give any important opinion about them. As to tobacco, my strong hope is that my own sons will never use it; but if they should develop peculiar and excitable nerves, or become very emotional, or have much trouble, it is so likely that they might take to some worse habit that I would prefer they should smoke. M. D. CONWAY. February 22, 1882. REV. W. H. DALLINGER, F. R. S. I am not a pledged abstainer: I have used both tobacco and alcohol in various forms. Neither is at all necessary to my vigour of either body or mind. My use of tobacco has been but slight. I have never Used alcohol for years. I could never think deeply after the use of tobacco; I have felt a quickening of thought at times after a slight use of good wine; but I know, from physiological evidence, what practice has certainly proved, that no permanent benefit to either body or mind must be sought from its use. I have employed it with great benefit at times--that is, where it was better to afford the exhaustion following a mere stimulant, than to submit to an exhaustion which the stimulant could for the moment counteract. This is the only advantage, save to the palate, that I have known to be derived personally from the use of alcohol. W. H. DALLINGER. February 11, 1882. PROFESSOR DARWIN. I drink a glass of wine daily, and believe I should be better without any, though all doctors urge me to drink wine, as I suffer much from giddiness. I have taken snuff all my life, and regret that I ever acquired the habit, which I have often tried to leave off, and have succeeded for a time. I feel sure that it is a great stimulus and aid in my work. I also daily smoke two little paper cigarettes of Turkish tobacco. This is not a stimulus, but rests me after I have been compelled to talk, with tired memory, more than anything else. I am 73 years old. CH. DARWIN. February 9, 1882.