The aorta, C, Plates 1 and 2, is behind the upper half of the sternum, from which it is separated by the pericardium, D, Plate 1, the thin edge of the lung, and the mediastinal pleurae, U E, Plate 1, &c. If the heart be injected from the abdominal aorta, the aortal arch will flatten against the sternum. Pulmonary space would not be opened by a penetrating instrument passed into the root of the neck in the median line above the sternum, at L, Plate 1. But the apices of both lungs would be wounded if the same instrument entered deeply on either side of this median line at K K. An instrument which would pierce the sternum opposite the insertion of the second, third, or fourth costal cartilage, from H downwards, would transfix some part of the arch of the aorta, C, Plate 1. The same instrument, if pushed horizontally backward through the second, third, or fourth interspaces of the costal cartilages close to the sternum, would wound, on the right of the sternal line, the vena cava superior, G, Plate 1; on the left, the pulmonary artery, B, and the descending thoracic aorta. In the healthy living body, the thoracic sounds heard in percussion, or by means of the stethoscope, will vary according to the locality operated upon, in consequence of the variable thickness of those structures (muscular and osseous, &c.,) which invest the thoracic walls. Uniformity of sound must, owing to these facts, be as materially interrupted, as it certainly is, in consequence of the variable contents of the cavity. The variability of the healthy thoracic sounds will, therefore, be too often likely to be mistaken for that of disease, if we forget to admit these facts, as instanced in the former state. Considering the form of the thoracic space in reference to the general form of the trunk of the living body, I see reason to doubt whether the practitioner can by any boasted delicacy of manipulation, detect an abnormal state of the pulmonary organs by percussion, or the use of the stethoscope, applied at those regions which he terms coracoid, scapulary, subclavian, &c., if the line of his examination be directed from before backwards. The scapula, covered by thick carneous masses, does not lie in the living body directly upon the osseous-thorax, neither does the clavicle. As all antero-posterior examination in reference to the lungs external to the points, I I, between the shoulders cannot, in fact, concern the pulmonary organs, so it cannot be diagnostic of their state either in health or disease. The difficulties which oppose the practitioner's examination of the state of the thoracic contents are already numerous enough, independent of those which may arise from unanatomical investigation. DESCRIPTION OF PLATES 1 & 2. PLATE 1. A. Right ventricle of the heart. B. Origin of pulmonary artery. C. Commencement of the systemic aorta, ascending part of aortic arch. D. Pericardium investing the heart and the origins of the great bloodvessels.