_Pathology._ Asthma is generally attributed to spasm of the bronchial muscles (Williams), and though recent observations have failed to sustain this it must be admitted that in the majority of cases it is of decided neurotic origin. Again it is attributed to erythematous swelling in patches of the bronchial mucosa, (Clark). Another theory is that it is a fibrinous inflammation of the mucosa of the bronchioles, the tenacious exudate blocking the tubes more or less completely and relief coming with a more diffluent secretion. Berkart found a streptococcus in the sputa which he supposed to be the final cause. Again it has been held to depend on the circulation in the blood of deleterious matters introduced during digestion. Again it has been attributed to a neurosis roused by constipation and the accumulation of irritant matters in the intestine. Whatever local conditions may be operative, there can be no doubt that in dogs it is almost exclusively confined to those kept indoors, overfed, without exercise, plethoric and constipated. The disease seems to originate in and persist by nervous disorder propagated from the digestive organs. A change of diet or any disturbing cause may bring on a paroxysm. _Symptoms._ The disease is one of pet dogs, kept in towns, deprived of exercise, fresh air, and of the opportunity to relieve the bowels at will, and gorged with highly spiced meats, and sweets at least three times a day. Sluggishness and obesity are marked characteristics of the dog when first attacked though in the advanced stages the violence of the paroxysms and their frequent recurrence may have induced extreme emaciation. The affection is usually ushered in by a cough, at first slight, but soon becoming frequent, hard and sonorous, as in the early stages of bronchitis. The cough becomes very troublesome and the breathing habitually labored, but at irregular intervals a paroxysm comes on which threatens death by suffocation. The dog stands or sits on his haunches with open mouth, pendent tongue and staring eyeballs, panting for breath, and has his condition aggravated by every change of position or other source of excitement. By the frequency and severity of the attacks may be estimated the danger of the patient. An examination in the intervals of the attacks detects some disturbance of the digestive organs. The tense and distended condition of the abdomen usually manifests the existence of overloaded stomach and bowels, of indigestion, tympany and constipation. Piles are often present as a result of long continued costiveness. The skin is dry and unthrifty, and often in patches denuded of hair. The teeth are covered with tartar and the breath fœtid. Retching is occasionally seen to occur during a violent access of coughing, but only a little glairy mucus is brought up.