Death may result from inanition and exhaustion, or from nervous prostration and poisoning. The affection may be complicated by purulent arthritis, peritonitis, pneumonia, hepatitis, keratitis or laminitis. It may prove fatal in from three to ten days. _Mortality._ This is always high. For foals it has been set down at 80 per cent. of the numbers attacked, for calves at 54 to 90 per cent., and for lambs at 66 per cent. In 500 lambs Beresow found 300 attacked and 200 died. Kuleschow sets the losses at 30 to 40 per cent. of the lambs, and Cadeac advises that even the survivors should be fitted for the butcher as they are unfit for reproduction. _Lesions._ In foals these are mainly confined to the intestines which show a more or less extended area of redness and congestion with catarrhal or pseudomembranous exudate on the mucosa, and the submucous connective tissue is infiltrated softened and marked by intense punctiform redness. The epithelium is swollen, opaque and easily detached, and Peyers patches infiltrated and prominent. The blood in the intestinal vessels is incoagulable. Exudation into the peritoneum and softening of the liver are not infrequent. In calves the lesions are very similar, but the 4th stomach is usually implicated, the congestion and epithelial desquamation being most marked in the pyloric region. The contents of the intestines are mucopurulent, grayish, yellowish or red, and intensely fœtid. The follicles of the small intestine are red and projecting with an areola of congestion. Softening and even necrotic centers are found in the liver and kidneys and the mesenteric glands are swollen, red and softened. In lambs the lesions are nearly the same in the 4th stomach, intestine, lymph glands, liver and kidneys. There is usually marked emaciation and the spleen and nerve centres are anæmic.