Another series of circulatory disorders are liable to take place. The blocking of the vessels of the right bundle, tends to increase the blood pressure in the left bundle and the anterior one, and thus to determine congestions, paresis and inflammations in the small intestines, the second division of the double colon and the floating colon. The resulting inflammation and increased vascular tension may lead indirectly to implications of the brain and lung. Extravasations so extensive as to appear like blood clots may be present between the layers of the mesentery or in the mucosa and submucosa, and blood, liquid or coagulated, may have accumulated in the abdominal cavity. Blood effusion into the intestine gives a dark red coloration to the contents which are further mixed with distinct clots. The atonic bowels are always the seat of extensive fermentations and tympany. The microbes engaged in these fermentations and their toxins, are accountable for toxic changes occurring in the locally diseased parts and in distant organs. To this may be attributed the congestion and softening of the liver and the engorgements and hemorrhagic centres in the spleen. _Symptoms._ An animal, perhaps known to harbor the sclerostoma equinum, is suddenly attacked with violent and persistent colic. He trembles, paws, moves his hind feet uneasily, kicks the abdomen, throws anxious looks at the flanks, crouches, lies down, rolls, gets up, and at once gets down again. The intensity of the suffering rapidly increases, the face is drawn and pinched, the eye is extremely anxious, the patient no longer lies down, but throws himself down reckless of consequences, when down he is not quiet for an instant, but now on his breast, then on his side, then on his back, the limbs struggling and jerked violently, the head turned first to one side and then to the other, he is a picture of extreme agony. If made to walk the same indications continue; he walks with head down and limbs semiflexed ready to drop at any moment, and often he will drop suddenly in spite of every effort to keep him on his feet. The pulse is at first strong and full, but as extensive effusion takes place into the bowels or abdomen, or as the animal is poisoned by toxins, it becomes small, weak, and it may be imperceptible. Breathing is quick and catching, and the mucous membranes are dark red. Sweating which shows first about the elbows or flanks or back of the ears finally becomes general, the surface cold and the limbs especially so. Fæces may be passed at first, a few dry balls at a time from the floating colon or rectum, but soon they are suppressed entirely. Some patients strain frequently to micturate but pass little at a time.