Text book of veterinary medicine, Volume 3 (of 5)Law, James
Science
Text book of veterinary medicine, Volume 3 (of 5)
Law, James
Veterinary medicine
FATTY DEGENERATION OF THE KIDNEY: STEATOSIS OF THE KIDNEY.
Causes: age, overfeeding, idleness, atony, retention of urine.
Lesions: kidney enlarged, pale yellow, capsule loose, cut surface
glistening unctuous, oil globules in scrapings, granules soluble in
ether. Symptoms: in idle, overfed, obese, improved meat producing
breeds, closely confined, starchy or saccharine food, fatty granules
in urine, finally dropsies, anæmia, debility, sluggishness. Prognosis
unfavorable in advanced stage. Treatment: butcher, restricted regimen,
open air exercise, nitrogenous diet, crossing, diuretic food or drugs,
oil of turpentine, balsam copiaba. Palliation only.
Fatty degeneration of the kidneys is by no means unknown in the domestic
animals. It has been observed in dogs and cats (Rogers, Goubaux,
Vulpain, Trasbot). In dogs it has been erroneously set down as a
characteristic lesion of rabies. Like fatty degeneration of other
organs, it is also met with in old and overfed individuals of meat
producing breeds of animals, in which the tendency to early maturity and
rapid and excessive fattening has been fostered from generation to
generation. In man small, granular, fatty kidney is a common result of
chronic parenchymatous nephritis, and often coincides with fatty liver.
Chronic poisoning by arsenic or phosphorus is another cause, as it is of
fatty degeneration in other organs.
Vulpain has attributed it to a lack of active exertion and of general
tone, associated with excessive amylaceous feeding, sluggish, shallow
breathing and tardy elimination. Goubaux and Trasbot attach great
importance to the compulsory retention of urine in house dogs, cats and
horses. The damming back of the urine in the convoluted tubes and
glomeruli, temporarily arrests secretion, and the inactive and
compressed cells tend at once to granular and fatty degeneration.
_Lesions._ The gland is sensibly increased in size, and pale, yellowish
or straw yellow. The capsule is easily detached from the cortical
substance, contrary to what is the case in chronic productive
inflammation. The cortical substance is increased in thickness, and
pale, the pallor being largely in ratio with the duration or extent of
the fatty degeneration. The cut surface may be glistening and unctuous
to the touch. It is softer than usual, rather friable, and if scraped,
furnishes a serous or grayish pulp in which oil globules are prominent
features, together with granular epithelium and free granules that
dissolve readily in ether. Tubules are varicose and unequal at different
parts. The medullary portion has undergone little change. It may be
paler at certain points, with some shrinking of its substance and
increase of firmness.
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