You see at once that the secretion of the first hour is identical in the two cases both as regards quantity and digestive power, and only in the second is the secretory work differentiated according to the nature of the food. How are we to explain the secretion which takes place at the commencement? Is it not the same which we have already seen in the sham feeding experiments? Is not this first onrush of the stream of secretion the preliminary psychic juice? Unquestionably, gentlemen, this is the case, and we may convince ourselves of the fact in the most diverse ways. Above all, the following is clear: whatever occurs in the so-called sham feeding cannot wholly be absent in the case of normal feeding, since the former is nothing else than the isolated commencement of normal digestion. This justifiable inference is fully confirmed, if the secretion of the first hours after the administration of flesh and bread be compared with that after simple sham feeding. In the case of feeding with flesh and bread, the identically similar and high digestive power of the first hourly portions is striking, and this power coincides with what we have met in sham feeding. Further, if the quantity of juice from the miniature stomach during the first hour be compared with that produced by the non-resected part of the organ,--to do which we must multiply it by ten, since the resected _cul-de-sac_ is approximately one-tenth of the whole organ,--it is here again found that the quantity approximately corresponds to the mean values obtained by sham feeding. Finally, the depression in digestive power or quantity of juice (with flesh, decrease of digestive power; with bread, decline in the quantity of juice), which sets in soon after the taking of food, indicates that the two conditions are connected with the ingestion of food--_i. e._, with a transitory factor which soon passes away and gives place to other conditions. Our explanation becomes still more convincing when we take into consideration the effects of other foods. If you give the dog, for example, something else to eat which does not interest it to the same degree as flesh or bread, you will find the initial increase in quantity and strength of juice does not appear. Offer the animal milk, for example, which in sham feeding, especially if it does not last long, calls forth, as a rule, no secretion, or at all events only very little, and the rapid flow of the commencement--the already-mentioned initial rise--absolutely fails to appear. You have already seen the figures which deal with this matter; I think it necessary, however, to bring them forward again in order that you may be better able to compare them with the secretion after flesh and bread. The dog was given 600 c.c. of milk (experiment by Dr. Chigin). Hour. Quantity of juice. Digestive power. 1st 4.2 c.c. 3.57 mm. 2nd 12.4 ” 2.63 ”