We have now begun the analytical examination of the variations of our secretory curve. But owing to the importance of the matter we did not confine ourselves to conclusions which might be drawn from earlier investigations. We turned to new forms of experiment for further proof. Thus we divided the ordinary ration of flesh given to our dogs--400 grams--into four equal parts, which were administered at intervals of an hour and a half. (Experiments by Privat docent Kotljar and Dr. Lobassoff.) Each time after the dog received its 100 grams of flesh we were able to detect a rise both in the quantity and in the digestive power of the juice. The following table shows the figures in question: ══════════╤═══════════╤═══════════╤═══════════════════════ Half-hour │ Quantity │ Digestive │ periods. │ of juice. │ power. │ Remarks. ——————————┼———————————┼——————————-┼——————————————————————— 1st │ 3.1 c.c. │ 5.13 mm. │ 100 grms. flesh given. 2nd │ 5.0 ” │ 4.63 ” │ 3rd │ 4.7 ” │ 4.50 ” │ 4th │ 5.4 ” │ 4.88 ” │ 100 grms. ” ” 5th │ 5.5 ” │ 3.38 ” │ 6th │ 4.7 ” │ 2.75 ” │ 7th │ 6.0 ” │ 3.75 ” │ 100 grms. ” ” 8th │ 5.4 ” │ 2.50 ” │ 9th │ 5.9 ” │ 2.50 ” │ 10th │ 5.4 ” │ 3.88 ” │ 100 grms. ” ” 11th │ 5.3 ” │ 3.0 ” │ 12th │ 4.2 ” │ 2.5 ” │ ——————————┴———————————┴——————————-┴————————————————————————— In the curve which follows, only the variations of digestive power are represented. It is clear that the increase, both of digestive power and of juice volume, is connected with the act of taking in food. It appeared of interest definitely to determine the volume and properties of the secretion called forth by the act of eating in the dog with the isolated stomach. We endeavoured, therefore, at the beginning, to imitate the conditions of sham feeding as they occurred in the case of the dog with divided œsophagus. In addition to the fistular orifice leading into the isolated miniature stomach, another was opened into the main portion of the organ. If we now fed the dog in the ordinary way with small pieces of flesh, these were received back again at the orifice of the latter fistula, covered with saliva. Precisely as in sham feeding, after five minutes the juice began to flow simultaneously, from both the large and small stomachs. The secretion ran a corresponding course in the two cavities and ceased at the same length of time in both after the administration of food was stopped. Here is an instance taken from such an experiment performed by Dr. Lobassoff. [Illustration: FIGURE 1.--Curve of digestive power constructed from the foregoing table.]