Imagine, on the other hand, any one worn out with the greatest pains of mind and body which can possibly befal a man, without any hope being held out to him that they will hereafter be lighter, when, besides, he has no pleasure whatever either present or expected; what can be spoken of or imagined more miserable than this? But if a life entirely filled with pains is above all things to be avoided, then certainly that is the greatest of evils to live in pain. And akin to this sentiment is the other, that it is the most extreme good to live with pleasure. For our mind has no other point where it can stop as at a boundary; and all fears and distresses are referable to pain: nor is there anything whatever besides, which of its own intrinsic nature can make us anxious or grieve us. Moreover, the beginnings of desiring and avoiding, and indeed altogether of everything which we do, take their rise either in pleasure or pain. And as this is the case, it is plain that everything which is right and laudable has reference to this one object of living with pleasure. And since that is the highest, or extreme, or greatest good, which the Greeks call τέλος, because it is referred to nothing else itself, but everything is referred to it, we must confess that the highest good is to live agreeably. XIII. And those who place this in virtue alone, and, being caught by the splendour of a name, do not understand what nature requires, will be delivered from the greatest blunder imaginable if they will listen to Epicurus. For unless those excellent and beautiful virtues which your school talks about produced pleasure, who would think them either praiseworthy or desirable? For as we esteem the skill of physicians not for the sake of the art itself, but from our desire for good health,—and as the skill of the pilot, who has the knowledge how to navigate a vessel well, is praised with reference to its utility, and not to his ability,—so wisdom, which should be considered the art of living, would not be sought after if it effected nothing; but at present it is sought after because it is, as it were, the efficient cause of pleasure, which is a legitimate object of desire and acquisition. And now you understand what pleasure I mean, so that what I say may not be brought into odium from my using an unpopular word. For as the chief annoyances to human life proceed from ignorance of what things are good and what bad, and as by reason of that mistake men are often deprived of the greatest pleasures, and tortured by the most bitter grief of mind, we have need to exercise wisdom, which, by removing groundless alarms and vain desires, and by banishing the rashness of all erroneous opinions, offers herself to us as the surest guide to pleasure. For it is wisdom alone which expels sorrow from our minds, and prevents our shuddering with fear: she is the instructress who enables us to live in tranquillity, by extinguishing in us all vehemence of desire.