The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
Certain stimulant Eliminatives are employed for the purpose of checking
mucous fluxes, and so far simulate the action of true Astringent
medicines. Thus we administer, with more or less advantage, Aromatics in
diarrh[oe]a; Cubebs, Copaiba, and Turpentine, in gonorrh[oe]a; and
Balsam of Peru, and other oleo-resins, in Catarrhal affections. These
medicines all act upon and pass through the glands of the several mucous
surfaces which they affect: while so doing, they stimulate the healthy
function and secretion of the gland, and cause it to displace the morbid
one. Dr. Williams thinks that they first cause dilatation of the vessels
of a gland, and that this is followed by contraction. There is no
apparent reason why the latter effect should succeed the former. But
supposing contraction to take place in this way, then these medicines
would be true Astringents. But it cannot be so, for they do not diminish
any of the natural secretions, but, on the contrary, increase them.
Turpentine, Cubebs, and Copaiba, are Diuretics, and it is possible that
while passing out in the urine they may simply stimulate the mucous
surface of the inflamed urethra, and excite it to a healthy action.
These volatile oils are incapable of exerting a true astringent action.
On the supposition that it is really an Astringent, Turpentine has been
often prescribed as a remedy for hæmorrhages in different parts of the
body. But it has very much disappointed the expectations that were
entertained of its efficacy.
General Stimulants may act indirectly as styptics to a mucous surface,
when relaxed and bleeding on account of an atonic condition of the
nerves by which the contraction of the minute vessels is maintained.
Alcohol, in large quantity, coagulates albumen, and it may thus act as a
true Astringent when applied externally.
Some Neurotic medicines diminish secretions in a way which is not well
understood. The chief of these is Opium, which particularly diminishes
the secretion of the bowels. Attempts have been made to explain this by
an influence possessed by Morphia on the process of Endosmosis, but they
are not satisfactory. Some little light may perhaps be thrown upon the
matter by a consideration of the other operations of Opium; but it is
difficult to explain it decisively in any way.
PROP. X.--_That a fourth class of medicines, called_ ELIMINATIVES, _act
by passing out of the blood through the glands, which they excite to the
performance of their functions_.
In this Fourth Class are included all the medicines which tend in a
direct manner to increase secretion. They have received various
appellations: some authors have called them special Stimulants; others,
as Dr. Duncan, have named them Evacuants; while Dr. Pereira entitles
them Eccritics.
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