The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
It was some time ago supposed that the fæces consisted simply of those
parts of the food which remained unabsorbed, and that all Purgative
medicines alike acted by exciting the peristaltic motion of the bowels,
and causing thus the ejection of these undigested matters. Such an
opinion is now rarely maintained. Although very little is known of the
separate functions of the glands of the intestinal mucous membrane, yet
it is generally supposed that the fæcal matters consist in great part of
excrementitious substances which are separated by their means from the
blood. The excretion of fæces continues when no food is taken. It is
known to go on with starving men, and with patients in fever. Liebig
argues for the secretion of the greater part of the fæces, on the ground
that they contain nitrogenous matters, whereas all the nitrogenous parts
of the food should be absorbed for the purposes of nutrition. Thus these
are probably the excreted products of changes in the system, which it
is the province of the bowels to separate from the blood. (_Anim. Chem._
p. 156.) The odour of these matters is partly owing to sulphuretted
hydrogen, or hydrosulphate of ammonia, both of which are the products of
animal decomposition. On account of their presence a black colour is
communicated to the fæces by the internal administration of the salts of
Iron.
It seems to me to be probable that the constituents of the living as
well as of the dead body are constantly subjected to the control of
chemical laws, and undergoing destruction and change. Some products of
these changes in an early stage are eliminated in the urine; but in
great part they go on to actual putrefaction. The products of this,
which are of an offensive character, are apparently discharged from the
body through the follicles and glands of the intestines. We find that
this decomposition is promoted and accelerated by heat, in the same way
as with dead animal matter. For this reason it appears that the natives
of warm climates excrete a much larger quantity of fæces than the
dwellers in colder latitudes; and they are also more subject to
Dysentery, Diarrh[oe]a, and Cholera, on account of the extra work thrown
upon their intestines. A similar explanation may perhaps be assigned to
a curious fact noticed some time ago by Mr. Curling--viz., that acute
ulceration of the duodenum is a frequent consequence of severe
superficial burns. A quantity of gangrenous or decomposing matter may in
such a case be carried from the surface into the circulation.
Public-domain text, read in full here on John Shaqi.
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