The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
The influence of Antimony on the glandular organs is indirectly but
powerfully intensified by its nauseant action. In small doses it is a
simple Expectorant; in nauseant doses, it assists expectoration by
relaxing the bronchial tubes, and diminishing the number of the
respirations. In a small dose it is Diaphoretic; but in large doses it
may cause copious sweating, by favouring the absorption of fluid into
the blood, and dilating the capillaries and pores of the sudorific
glands. In inflammatory habits a small addition of Tartar Emetic forms a
powerful adjunct to a purgative dose; for by it the absorption of the
other medicine is assisted, and at the same time an over-tonicity of the
muscular fibre of the intestine may be diminished. But in relaxed
conditions of the system, where the intestine is apt to be over-dilated,
and Catharsis is favoured by Tonic medicines,--Tartar Emetic would
hinder it.
Ipecacuanha, a vegetable substance, resembles Antimony in all its
operations, excepting its blood-action. It is less potent as a
Neurotic; less efficacious as a Diaphoretic; but excels it as an
Expectorant. (_Vide_ pp. 93, 168, 185, 249, 283, 298.)
MERCURY.
Class I. Div. II. Ord. I. ANTIPHLOGISTICA.
Class I. Div. II. Ord. II. ANTISYPHILITICA.
Class IV. Ord. III. CATHARTICA.
Class IV. Ord. IV. CHOLAGOGA.
There are three principal forms in which this medicine may be exhibited.
Blue pill contains the metal itself in a finely divided state, as well
as a small quantity of the oxide. Calomel is an insoluble Chloride of
Mercury. From the great similarity that exists between the action of
these two it seems likely that they are reduced by the gastric fluid to
the same condition. Both must be rendered soluble (p. 88) before they
can be absorbed. Probably they are both absorbed in combination with the
acid of the stomach.
Bichloride of Mercury is soluble in water, and probably absorbed
unchanged. It differs from the other two as a medicine, partly, but not
entirely, on account of its solubility. The dose required is smaller,
for it is much more powerful. It is also much more irritant, being in
large doses a corrosive poison, and often producing soreness of the
throat and of the urinary passages. Thirdly, it is less likely to
produce salivation. It is more adapted for chronic than for acute
diseases.
As Hæmatic medicines, Mercurials have a double action. They counteract
inflammation in general, and the poisons of Syphilis in particular. They
thus belong to the first and second orders of Catalytics.
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