The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
Mercury deteriorates the blood, diminishing in it the amount of fibrine
and corpuscles. As an anti-inflammatory agent, it may be thus compared
with Antimony and Blood-letting. The immediate effect of Blood-letting
is mechanical; that of Antimony, nervous; that of Mercury, hæmatic.
Blood-letting weakens the force of the heart by diminishing the pressure
on the vessels; Antimony diminishes the pressure on the vessels by
weakening the force of the heart; and Mercury does both of these things,
by impoverishing the blood. Thus all of them favour absorption, and
counteract effusion; but, from its nature, the action of Mercury is
slower than that of the others, and for the same reason more lasting. To
produce this action on the blood, the Mercurial should be continued
until some effect on the mouth is perceived, but not so as to cause
copious salivation. This symptom is a sign that the blood is
sufficiently saturated with the medicine. This point will be sooner
reached if the Mercury be conjoined with Opium, so as to prevent it from
passing out directly by the bowels. Any ill result is less likely to
occur if the patient be kept warm and quiet while under the influence of
the medicine. On account of the durable and effectual nature of its
action, Mercury is of great use in preventing the process of effusion,
and in causing the absorption of effused products. It is thus employed
with advantage in Pleurisy, and in other membranous inflammations. Next
to these, it is most useful in inflammations of the liver and brain. It
is inferior to Antimony in fevers and rapid inflammations, because
slower in operation, and without any direct action on the nervous
system.
In cases of primary Syphilis, Mercury is by far the best medicine with
which we are acquainted. It should be used in all cases except where
there is deep-rooted scrofula, or marked debility, or a sloughing and
irregular condition of the primary sore. (Dr. Pereira.) It should always
be given in Iritis. In Periostitis, and secondary eruptions, Iodide of
Potassium is generally preferable.
Mercury, being unnatural to the blood, passes at length out of the
system through the glands, and acts as an Eliminative. Like Antimony it
tends to increase all the secretions in the body. But whereas Antimony
acts especially on the secretions of the skin and pulmonary membrane,
Mercury tends particularly to excite the functions of the liver and
bowels, being Cathartic and Cholagogue. Of its true eliminative action
we have better proof than has yet been obtained in the case of Antimony;
for Mercury has been found to pass into the alvine excretions, by M.
Lehmann; and discovered in the bile of dogs to whom it had been
administered, by M. Buchheim.
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