It is a pleasure to turn from a contemplation so depressing to the spirits of one who has labored hopefully for years to secure a just and rational treatment of his favorite study at the hands of Pharmaceutical educators, to Part II. of Prof. Sayre’s book, a work so bright and practical, so replete with new and helpful ideas in the teaching of practical Pharmacognosy, and so full of information, both standard and exceptional, though unhappily marred by many errors, as to secure for it at once a prominent place upon the shelves of the “Handy Book Case.” The principle is here adhered to of making a single volume do duty as a text-book of Pharmacognosy and of “Materia Medica,” as the latter term is commonly used. We have never looked upon this method as being practicable, but Prof. Sayre resorts to a most ingenious device never before resorted to, by which it must be admitted that better results have been obtained than have previously been reached. What might be called a “Pharmacognostical Key,” or a synopsis of Pharmacognosy, is presented separately in advance of the main body of Part II. Here the drugs are numbered to correspond with the consecutive numbering prominently displayed under the second arrangement, that by natural orders, the proper method for retaining and displaying the natural relationships of active constituents and medicinal properties. The “Pharmacognostical Key” appears to us a failure in its practical workings, owing to indefinite characterization, by reference to taste only of the headings. If a drug is both bitter and aromatic, we have to look for it both in Class I. and Class III. A bifurcating key is here required, or better, we might take a combination of characters for each heading. On the whole, this key, while elaborate and very full, and subject to great improvement by a few trifling changes, we must regard as inferior to that of Maisch’s text-book. Prof. Sayre very sensibly omits all attempt to classify volatile oils, except by indicating their sources.