Accordingly, June 8th, the combs of the two condemned colonies were melted into wax, the honey drained over and scalded, and the bees, after a confinement of forty hours, were treated like new swarms; and now, September 18th, are perfectly healthy and in fine condition for winter. I will not occupy your valuable space with all the details of my experiments and fights (which lasted through three months) with the trials of doses of different strengths and kinds, with old comb and new, with young queens and old ones, and with no queen at all, and how, in doing this, I was obliged to keep up the strength of the colony for fear of robbers and of spreading the disease to my neighbors. Suffice it to say, that after two months I had made no apparent headway, although still determined to “fight it out on this line, if it took all summer” and my last hive. In fact, I devoted my apiary to the study of this disease, and, perhaps, death. Starting with, and holding to the theory that foulbrood is contagious only by the diffusion of living germs of feeble vitality, (and I was strengthened in my conjecture in microscopical examinations, by finding the dead larvæ filled with nucleated cells,) I determined to try those remedies which have the power of destroying the vitality of these destructive germs, these living organisms. And no remedies seemed to me more potent than carbolic acid and hyposulphite of soda. At first I used both, making one application of each, with an interval of one day, and with apparent benefit. But, attributing the improvement to the more powerful of the two, I abandoned the hyposulphite and used the carbolic acid alone, and I was so infatuated with the idea of its superiority, that I did not give it up until three of the four hives had become so hopelessly diseased, that the combs were destroyed and the colonies treated to new combs (as it was late in the season,) and freely fed with sugar and water. These are now in good condition for winter. The fourth hive was carried a mile away, the queen caged, and the colony strengthened with a medium sized second swarm. After all the brood, which was advanced, had left the cells, I transferred the colony to a clean hive; thoroughly sulphured the old hive with burning sulphur, and stored it away in a safe place for future experiments. I now thought my apiary free from the pest; but on thoroughly examining the whole, three new cases of foulbrood were found--one very badly affected, and two slightly so, with perhaps twenty to forty cells diseased and perforated. Entered according to Act of Congress, in the year 1870, by Samuel Wagner, in the office of the Librarian of Congress, at Washington.