this overmuch waking as a principal cause. MEMB. III. SUBSECT. I.—_Passions and Perturbations of the Mind, how they cause Melancholy_. As that gymnosophist in [1571]Plutarch made answer to Alexander (demanding which spake best), Every one of his fellows did speak better than the other: so may I say of these causes; to him that shall require which is the greatest, every one is more grievous than other, and this of passion the greatest of all. A most frequent and ordinary cause of melancholy, [1572] fulmen perturbationum (Picolomineus calls it) this thunder and lightning of perturbation, which causeth such violent and speedy alterations in this our microcosm, and many times subverts the good estate and temperature of it. For as the body works upon the mind by his bad humours, troubling the spirits, sending gross fumes into the brain, and so per consequens disturbing the soul, and all the faculties of it, [1573]———Corpus onustum, Hesternis vitiis animum quoque praegravat una, with fear, sorrow, &c., which are ordinary symptoms of this disease: so on the other side, the mind most effectually works upon the body, producing by his passions and perturbations miraculous alterations, as melancholy, despair, cruel diseases, and sometimes death itself. Insomuch that it is most true which Plato saith in his Charmides, omnia corporis mala ab anima procedere; all the [1574]mischiefs of the body proceed from the soul: and Democritus in [1575]Plutarch urgeth, Damnatam iri animam a corpore, if the body should in this behalf bring an action against the soul, surely the soul would be cast and convicted, that by her supine negligence had caused such inconveniences, having authority over the body, and using it for an instrument, as a smith doth his hammer (saith [1576]Cyprian), imputing all those vices and maladies to the mind. Even so doth [1577]Philostratus, non coinquinatur corpus, nisi consensuanimae; the body is not corrupted, but by the soul. Lodovicus Vives will have such turbulent commotions proceed from ignorance and indiscretion. [1578]All philosophers impute the miseries of the body to the soul, that should have governed it better, by command of reason, and hath not done it. The Stoics are altogether of opinion (as [1579]Lipsius and [1580]Picolomineus record), that a wise man should be ἀπαθής, without all manner of passions and perturbations whatsoever, as [1581]Seneca reports of Cato, the [1582] Greeks of Socrates, and [1583]Io. Aubanus of a nation in Africa, so free from passion, or rather so stupid, that if they be wounded with a sword, they will only look back. [1584]Lactantius, 2 instit., will exclude fear from a wise man: others except all, some the greatest passions. But let them dispute how they will, set down in Thesi, give precepts to the contrary; we find that of [1585]Lemnius true by common experience; No mortal man is free from these perturbations: or if he be so, sure he is either a god, or a block.