[176] For an account of the life-cycle of _Eimeria stiedæ_ consult Wasielewski, Th. von (1904), “Studien und Photogramme zur Kenntnis der pathogenen Protozoen,” Heft. 1 (Coccidia), 118 pp., 7 plates, Leipzig: J. A. Barth. Also, Metzner, R. (1903), _Arch. f. Protistenk._, ii, p. 13. Young rabbits often die of intestinal coccidiosis before infection of the liver occurs. The repeated schizogony of _Eimeria stiedæ_ in the gut is sufficient to cause death. [Illustration: FIG. 74.--_Eimeria stiedæ_. Section through coccidian nodule in infected rabbit’s liver. × 55.] The disease of cattle popularly known as “red dysentery” is also ascribed to the action of _Eimeria stiedæ_. The fæces of infected cattle show blood clots of various sizes and in severe cases watery diarrhœa is present. Acute cases end fatally in about two days. Numerous oöcysts, considered to be those of _Eimeria stiedæ_, occur in the fæces, and there is a heavy infection of the gut, especially the large intestine and rectum, all stages of the parasite being found in the epithelium. It is suspected that cattle contract the disease by feeding on fresh grass contaminated with oöcysts. The disease is recorded from Switzerland and from East Africa. As before mentioned, _Eimeria stiedæ_ is considered to be the organism found in a few cases in man, possibly acquired by eating the insufficiently cooked livers of diseased rabbits. These cases may now be described. (_a_) *Human Hepatic Coccidiosis.* (1) Gubler’s Case. A stone-breaker, aged 45, was admitted to a Paris hospital suffering from digestive disturbances and severe anæmia. On examination the liver was found to be enlarged and presented a prominent swelling, which was regarded as being due to Echinococcus. At the autopsy of the man, who succumbed to intercurrent peritonitis, twenty cysts were found averaging 2 to 3 cm. in diameter, and one measuring 12 to 15 cm. The caseous contents consisted of detritus, pus corpuscles, and oval-shelled formations, which were considered to be Distoma eggs, but which, in accordance with Leuckart’s conjecture, proved to be Coccidia.[177] [177] Gubler, A., “Tumeurs du foie déterm. par des œufs d’helm....” _Mem. Soc. Biol._, Paris, 1858, v, 2; and _Gaz. med. de Paris_, 1858, p. 657; Leuckart, R., _Die menschl. Paras._, 1863, 1ST edition, i, pp. 49, 740. (2) Dressler’s Case (Prague). Relates to three cysts, varying from the size of a hemp-seed to that of a pea, and containing Coccidia, found in a man’s liver.[178] [178] Leuckart, R., _Die menschl. Paras._, 1863, 1st edition, i, p. 740. (3) Sattler’s Case (Vienna). Coccidia were in this case observed in the dilated biliary duct of a human liver.[179] [179] Leuckart, R., _Die Paras. d. mensch._, 1879, 2nd edition, p. 281. (4) Perls’ Case (Giessen). Perls discovered Coccidia in an old preparation of Sömmering’s agglomerations.[180] [180] Leuckart, R., _ibid._, p. 282.