Certain nematodes show very clearly to what devious courses parasitism may lead. The _Atractonema gibbosum_, the life-history of which has been described by R. Leuckart, and which lives in the larvæ and pupæ of a dipterous insect (_Cecidomyia_), exhibits, in its early stage, the ordinary characteristics of other threadworms. A few weeks later--the males having died off immediately after copulation--the females are transformed into spindle-shaped bodies, the mouth and anus of which are closed. They carry with them an irregularly shaped appendage, in which the segmenting ova are situated, and in which the further conditions of life of the _Atractonema_ are accomplished. A minute examination has demonstrated that this appendage is the prolapsed and enlarged vagina of the animal which has become merely a supplementary attachment. The conditions present in the _Sphærularia_, the nematoid nature of which was long undiscovered, are still more remarkable. It was only when Siebold proved that typical nematodes were hatched from their eggs that their nature was recognized. The nematodes thus produced have not the slightest resemblance to the parent. The researches of Lubbock, A. Schneider, and more particularly of R. Leuckart, have shown that what we call _Sphærularia bombi_ is not an animal but merely an organ--the vagina--of a nematode worm. This vagina at first grows, sac-like, from the body of the tiny nematode; it gradually assumes enormous dimensions (2 cm. in length); it contains the sexual organs and parts of the intestine. The remaining portion of the actual animal then becomes small and shrivelled; it may be easily overlooked, being but an appendage to the vagina with its independent existence, and it finally disappears altogether. The GREAT FERTILITY of parasites is another of their peculiarities, though this may be also the case to a certain degree with some of the free-living animals, the progeny of which are likewise exposed to enormous destruction. More remarkable, however, is the fact that the young of the endoparasites only very exceptionally grow to maturity by the side of their parents. Sooner or later they leave the organ inhabited by the parents, frequently reach the open, and after a shorter or longer period of free existence seek new hosts. During their free period, moreover, a considerable growth may be attained, or metamorphosis may take place, or even multiplication. In the exceptional cases in which the young remain within the same host, they nevertheless usually quit the organ inhabited by the parents. They likewise rarely attain maturity within the host inhabited by the parents, but only, as in other cases, after having gained access to fresh hosts.