Another case, in my own mouth. The second left superior molar had for years stood alone, which facilitated a thorough cleansing upon all sides: I was therefore somewhat surprised at what appeared to be the development of a case of pyorrhoea alveolaris. The tooth continued sore, becoming looser, until its removal was a necessity. Neuralgia, and all the symptoms of a dying pulp had been present for three months. On extracting the tooth the nerve was found to be alive, and not much congested. The three roots were absorbed upon their inner surfaces. Exploration of the socket revealed the fact that a portion of the process enclosed by the three roots had been entirely absorbed. As the socket did not close in the usual time, I made an examination, and the probe revealed the presence of the missing wisdom tooth. The tooth has still continued to come down, but has not yet reached the gum line. Another case in my own mouth is of interest: the result of wearing a wedge for three weeks between the first molar and the second bicuspid, on the right side. Some time after the tooth was filled, the first bicuspid became sensitive to heat and cold, and showed symptoms of peridental inflammation. Had a patient come to me describing the conditions of this tooth, I think I should have at once drilled into it, and applied the arsenic, but as it was in my own mouth I did nothing; and for fifteen months this tooth gave more or less trouble, but finally these disagreeable symptoms subsided, and the tooth is now apparently perfectly well. * * * * * DR. G. L. CURTIS, of Syracuse, has been acting as Dr. Garrettson's assistant in oral surgery this winter, in Philadelphia. CAMPHO-PHENIQUE.[2] BY J. W. DOWNEY, M.D., STATE CENTRE, IOWA. _Mr. President and Gentleman_: Campho-phenique is a germicide and antiseptic or nothing, therapeutically considered; and discussing its properties necessarily opens the entire subject of germicides and antiseptics, a subject fraught with peril to the writer or speaker, especially if he is not a practical chemist, pathologist, and microscopist. Nothing in pathology is better established than the fact that certain microscopic germs cause disease, and no point in therapeutics is better known than the fact that a few drugs will, within the limit of safety, destroy these germs, and thus most effectually cure or prevent disease.