Whenever I have found out that I have blundered, or that my work has been imperfect, and when I have been contemptuously criticised, and even when I have been overpraised, so that I have felt mortified, it has been my greatest comfort to say hundreds of times to myself that “I have worked as hard and as well as I could, and no man can do more than this.” I remember when in Good Success Bay, in Tierra del Fuego, thinking (and, I believe, that I wrote home to the effect) that I could not employ my life better than in adding a little to Natural Science. This I have done to the best of my abilities, and critics may say what they like, but they cannot destroy this conviction. During the two last months of 1859 I was fully occupied in preparing a second edition of the ‘Origin,’ and by an enormous correspondence. On January 1st, 1860, I began arranging my notes for my work on the ‘Variation of Animals and Plants under Domestication;’ but it was not published until the beginning of 1868; the delay having been caused partly by frequent illnesses, one of which lasted seven months, and partly by being tempted to publish on other subjects which at the time interested me more. On May 15th, 1862, my little book on the ‘Fertilisation of Orchids,’ which cost me ten months’ work, was published: most of the facts had been slowly accumulated during several previous years. During the summer of 1839, and, I believe, during the previous summer, I was led to attend to the cross-fertilisation of flowers by the aid of insects, from having come to the conclusion in my speculations on the origin of species, that crossing played an important part in keeping specific forms constant. I attended to the subject more or less during every subsequent summer; and my interest in it was greatly enhanced by having procured and read in November 1841, through the advice of Robert Brown, a copy of C.K. Sprengel’s wonderful book, ‘Das entdeckte Geheimniss der Natur.’ For some years before 1862 I had specially attended to the fertilisation of our British orchids; and it seemed to me the best plan to prepare as complete a treatise on this group of plants as well as I could, rather than to utilise the great mass of matter which I had slowly collected with respect to other plants. My resolve proved a wise one; for since the appearance of my book, a surprising number of papers and separate works on the fertilisation of all kinds of flowers have appeared: and these are far better done than I could possibly have effected. The merits of poor old Sprengel, so long overlooked, are now fully recognised many years after his death.