The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic DevelopmentHertwig, Oscar
Science
The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic Development
Hertwig, Oscar
Developmental biology; Embryology; Genetics
Although the new evolution differs from the old in the points mentioned
above, the two theories obviously agree very closely in the nature of their
arguments and conclusions. When, to satisfy our craving for causality,
biologists transform the visible complexity of the adult organism into a
latent complexity of the germ, and try to express this by imaginary tokens,
by minute and complicated particles cohering into a system, they are making
a phantasmal image which, indeed, apparently may satisfy the craving for
causality (to satisfy which it was invented), but which eludes the control
of concrete thought, by dealing with a complexity that is latent, and
perhaps only imaginary. Thus, craftily, they prepare for our craving after
causality a slumbrous pillow, in the manner of the philosophers who would
refer the creation of the world to a supernatural principle.
But their pillow of sleep is dangerous for biological research; he who
builds such castles in the air easily mistakes his imaginary bricks,
invented to explain the complexity, for real stones. He entangles himself
in the cobwebs of his own thoughts, which seem to him so logical, that
finally he trusts the labour of his mind more than Nature herself.
'Experiment,' says Weismann in _The Germplasm_, 'is not the only way to
reach general views, nor is it always the safest means of discrimination,
although at first it seems conclusive....[3] It seems to me that in this
case we can draw more prudent conclusions from the general facts of
inheritance than from the results of experiments that are neither quite
clear nor undubious, although in themselves they are most valuable, and
deserve the most careful consideration. If one remembers what was said in
my section on the architecture of the germplasm as the basis of the theory
of determinants, it will be agreed with me that ontogeny must find its
explanation in evolution, and not in epigenesis.'[4]
I take up a more epigenetic position, and years ago I attacked evolutionary
doctrines in many of their modifications.[5] Thus, in the _Studien zur
Blätter Theorie_, published by Richard Hertwig and myself, I combated the
supposed law that the germinal layers histologically were primitive organs.
Next, in a pamphlet entitled _The Problem of Fertilisation: a Theory of
Heredity_, I attempted to disprove the principle of His that there were
organ-building foci in the germ. In my treatise _On Ovogenesis and
Spermatogenesis in the Nematodes_, I declared against the suppositions
involved in Weismann's doctrine of the germplasm, and sharply distinguished
the theory, simultaneously propounded by Strasburger and myself, that the
nucleus is the bearer of the hereditary material, from the evolutionistic
interpretation given it by Weismann.
Public-domain text, read in full here on John Shaqi.
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