The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic DevelopmentHertwig, Oscar
Science
The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic Development
Hertwig, Oscar
Developmental biology; Embryology; Genetics
The following will serve as examples of this. _Podophrya gemmipara_, an
Acinetan, in the adult condition is attached by a long stalk, while the
free end, at which is the mouth, is provided with suctorial tentacles. It
reproduces by giving rise to many little buds, ciliated on the upper
surface like free-swimming, hypotrichous infusoria. These, in appearance,
are quite unlike the parent organism, and, after a vagrant existence in the
water for some time, they attach themselves to a surface and produce a
stalk, tentacles with suctorial pseudopodia, and so for the first time
attain the maternal form.
Some Gregarines are large, jointed cells, divided into two pieces, a
protomerite and a deutomerite; they are clad with a cuticle, under which
lies a layer of muscular fibrils. After conjugation they encyst, the
nucleus divides, and they break up into numerous peculiarly-shaped
boat-like structures, (pseudonavicellæ), which afterwards are set free as
small, sickle-shaped embryos. These exceedingly small germ-cells
afterwards develop into the very different, adult gregarine-cells.
If the characters of a species be associated with a hereditary mass, an
actual substance that is handed on from the parent-cell to the offspring,
it is clear that the infusoria-like vagrant young of the Acinetan, and the
sickle-shaped embryos of the Gregarine possess it, although for some time
they are quite unlike the parent organism. For at last they become an
Acinetan or a Gregarine, exactly like the parent-cell from which they arose
as embryos.
These circumstances, among unicellular organisms, are a weighty indication
of the error of concluding, with Weismann, in the case of multicellular
forms, that because cells are unlike in outward appearance, the hereditary
mass, or, as I call it, the nuclear matter, within them is also unlike.
Such an assumption would involve us in the greatest contradictions. For the
supposition that the nucleus is the hereditary mass transmitting the
characters of the species necessitates the conclusion, in the case of
unicellular forms, that the hereditary mass remains in possession of all
the rudiments of the cell while it passes through the various phases of its
cycle of development. Otherwise, these phases would have to be acquired
anew in each case. We must, therefore, represent the possibilities of
exchange between the nucleus, in its capacity of bearer of the hereditary
mass, and the protoplasm as being such that all the rudiments are not
simultaneously in activity, but that some of them can remain latent for a
time.
SECOND GROUP OF FACTS.--THE LOWER MULTI-CELLULAR ORGANISMS.
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