The manner in which the Egg of the female is impregnated by the male Semen is curious and interesting. In its first state, while in the Ovary, there may be seen within it a little dot called the Germinal Vesicle. When the Egg is fully ripe, and just as it leaves the Ovary, this little dot is by some unknown process expelled, leaving an open passage to the very centre. The Egg is then ready for impregnation; for, on passing into the Womb, if the male Semen come in contact with it, one of the animalculæ instantly darts into this open passage and buries itself. All these curious operations of Nature have been discovered by the use of the Microscope, and they are not only very interesting, but are of great importance to mankind. It will be seen from these explanations of the principles of Impregnation, that a healthy woman may conceive under almost any circumstances—that the idea that a first and only connection would not impregnate is erroneous—that the most brutal violation may cause conception—in short, that if a female were rendered senseless by drugs, or by a blow upon the head, this would not prevent the impregnation of the Egg if the time were propitious. Sexual enjoyment of the female during connection may hasten the accomplishment of the desired end in various ways, but it is by no means necessary to impregnation or conception. Indeed, there are many females of cold temperament who seldom experience any very pleasing sensations during connection, and some who have no sexual desires at all. I knew a case in Hartford, Connecticut, many years ago, where a wealthy gentleman desired offspring. He had lost his Penis when quite a young man; but yet he was able, at times, to discharge Semen from the urinary passage. He was married after the loss of his private member, and lived with his wife—a very worthy woman—ten years, never dreaming that he could ever become a father. One day a physician banteringly told him of a similar case in Vienna, where the man had actually become a father by the use of a small glass syringe, with which he injected his Semen into the Vagina. It was a singular coincidence that this Hartford gentleman afterwards became the father of two interesting little ones. He had doubtless used the Syringe!