The two regents appeared before Charles VIII, one at Turin, one at Casale, each at the head of a numerous and brilliant court, and both glittering with jewels and precious stones. Charles, although he quite well knew that for all these friendly demonstrations they were both bound by treaty to his enemy, Alfonso of Naples, treated them all the same with the greatest politeness, and when they made protestations of friendship, asked them to let him have a proof of it, suggesting that they should lend him the diamonds they were covered with. The two regents could do no less than obey the invitation which was really a command. They took off necklaces, rings, and earrings. Charles VIII gave them a receipt accurately drawn up, and pledged the jewels for 20,000 ducats. Then, enriched by this money, he resumed his journey and made his way towards Asti. The Duke of Orleans held the sovereignty of Asti, as we said before, and hither came to meet Charles both Ludovico Sforza and his father-in-law, Hercules d’Este, Duke of Ferrara. They brought with them not only the promised troops and money, but also a court composed of the loveliest women in Italy. The balls, fetes, and tourneys began with a magnificence surpassing anything that Italy had ever seen before. But suddenly they were interrupted by the king’s illness. This was the first example in Italy of the disease brought by Christopher Columbus from the New World, and was called by Italians the French, by Frenchmen the Italian disease. The probability is that some of Columbus’s crew who were at Genoa or thereabouts had already brought over this strange and cruel complaint that counter balanced the gains of the American gold-mines.