Even as far back as the thirteenth century, indeed, lawless sea-rovers, mostly Bretons and Flemings, had infested the English Channel and the seas about Great Britain. In the sixteenth this mode of livelihood became the refuge for numerous young Englishmen, Catholic and Protestant, who, fleeing from the persecutions of Edward VI. and of Mary, sought refuge in French ports or in the recesses of the Irish coast, and became the leaders of wild roving bands living chiefly upon plunder. Among them during these persecutions were found many men belonging to the best families in England, and although with the accession of Elizabeth most of the leaders returned to the service of the State, the pirate crews remained at their old trade. The contagion spread, especially in the western counties, and great numbers of fishermen who found their old employment profitless were recruited into this new calling.[37] At the beginning of Elizabeth's reign we find these Anglo-Irish pirates venturing farther south, plundering treasure galleons off the coast of Spain, and cutting vessels out of the very ports of the Spanish king. Such outrages of course provoked reprisals, and the pirates, if caught, were sent to the galleys, rotted in the dungeons of the Inquisition, or, least of all, were burnt in the plaza at Valladolid. These cruelties only added fuel to a deadly hatred which was kindling between the two nations, a hatred which it took one hundred and fifty years to quench. The most venturesome of these sea-rovers, however, were soon attracted to a larger and more distant sphere of activity. Spain, as we have seen, was then endeavouring to reserve to herself in the western hemisphere an entire new world; and this at a time when the great northern maritime powers, France, England and Holland, were in the full tide of economic development, restless with new thoughts, hopes and ambitions, and keenly jealous of new commercial and industrial outlets. The famous Bull of Alexander VI. had provoked Francis I. to express a desire "to see the clause in Adam's will which entitled his brothers of Castile and Portugal to divide the New World between them," and very early the French corsairs had been encouraged to test the pretensions of the Spaniards by the time-honoured proofs of fire and steel. The English nation, however, in the first half of the sixteenth century, had not disputed with Spain her exclusive trade and dominion in those regions. The hardy mariners of the north were still indifferent to the wonders of a new continent awaiting their exploitation, and it was left to the Spaniards to unfold before the eyes of Europe the vast riches of America, and to found empires on the plateaus of Mexico and beyond the Andes. During the reign of Philip II. all this was changed. English privateers began to extend their operations westward, and to sap the very sources of Spanish wealth and power, while the wars which absorbed