The main part of the damage, however, was wrought by other than human means. In A.D. 542 there broke out in the empire a plague such as had not been known for three hundred years—the last similar visitation had fallen in the reign of Trebonianus Gallus, far back in the third century. This pestilence was one of the epoch-making events in the history of the empire, as great a landmark as the Black Death in the history of England. The details which Procopius gives us concerning its progress and results leave no doubt that it operated more powerfully than any other factor in that weakening of the empire which is noticeable in the second half of the sixth century. When it reached Constantinople, 5,000 persons a day are said to have fallen victims to it. All customary occupations ceased in the city, and the market-place was empty save for corpse-bearers. In many houses not a single soul remained alive, and the government had to take special measures for the burial of neglected corpses. “The disease,” says the chronicler, “did not attack any particular race or class of men, nor prevail in any particular region, nor confine itself to any period of the year. Summer or winter, North or South, Greek or Arabian, washed or unwashed—of such distinctions the plague took no account. A man might climb to the hill-top, and it was there; he might retire to the depths of a cavern, and it was there also.” The only marked characteristic of its ravages that the chronicler could find was that, “whether by chance or providential design, it strictly spared the most wicked.”(12) Justinian himself fell ill of the plague: he recovered, but was never his old self again. Though he persevered inflexibly to his last day in his scheme for the reconquest of the empire, yet he seems to have declined in energy, and more especially to have lost that power of organization, which had been his most marked characteristic. The chroniclers complain that he had grown less hopeful and less masterful. “After achieving so much in the days of his vigour, when he entered into the last stage of his life he seemed to weary of his labours, and preferred to create discord among his foes or to mollify them with gifts, instead of trusting to his arms and facing the dangers of war. So he allowed his troops to decline in numbers, because he did not expect to require their services. And his ministers, who collected his taxes and maintained his armies were affected with the same indifference.”(13)