The mutation, then, in so far as we have experimental knowledge of it, does not fulfill requirements of a specific change. It cannot even be regarded as an _elementary step_ in the direction of such a change. With this admission, De-Vriesianism becomes obsolete, descending like its predecessors, Lamarckism and Darwinism, into the charnel-house of discarded systems whose value is historic, but no longer scientific. When we enquire into the reason of this common demise of all the classic systems of transformism, we find it to reside in the progress of the new science of Mendelian genetics, whose foundations were laid by an Augustinian monk of the nineteenth century. Six years after the appearance of Darwin’s “Origin of Species,” Gregor Johann Mendel published a short paper entitled “Versuche über Pflanzen-hybriden,” which, unnoticed at the time by a scientific world preoccupied with Darwinian fantasies, was destined, on its coming to light at the beginning of the present century, to administer the final _coup de grace_ to all the elaborate schemes of evolution that had preceded or followed its initial publication. It took half a century, however, before the dust of Darwinian sensationalism subsided sufficiently, to permit the “rediscovery” of Mendel’s solid and genuine contribution to biological science. But the Prälat of the abbey at Brünn never lived to see the day of his triumph. The true genius of his century, he died unhonored and unsung, a pretender being crowned in his stead. For Coulter says of Darwin: “He died April 19, 1882, probably the most honored scientific man in the world.” (_Evolution_, 1916, p. 35.) Within the small dimensions of the paper, of which we have spoken, Mendel had compressed the results of years of carefully conceived and accurately executed experimentation reduced to precise statistical form and interpreted with a penetrating sagacity of the highest order. It is no exaggeration to say that his discovery has revolutionized the science of biology, giving it, for the first time, mathematical formulas comparable to those of chemistry. His two laws of inheritance, namely, the law of segregation and the law of independent assortment of characters, have, as previously intimated, become the basis of the new science of Genetics. His analysis of biparental reproduction has interpreted for us the cytological phenomena of synapsis, meiosis, and syngamy, has explained for us the instability of hybrids, has placed Weismann’s speculations concerning the autonomy and continuity of the germ plasm on a firm basis of experimental fact, has clarified all our notions respecting the mode and range of hereditary transmission, and has, in a word, opened our eyes to that new and hitherto unexplored realm of nature which Bateson calls “the world of gametes.”