2. THE INSTINCTIVE AVERSION TO ANY KIND OF POISON CAN BE PERVERTED INTO AN UNNATURAL CRAVING AFTER THE SAME SUBSTANCE.—Poisons are either repulsive or insipid. Arsenic, sugar of lead, and antimony, belong to the latter class. To the first-born children of earth certain mineral poisons were decidedly _out of the way substances_, against which nature apparently thought it less necessary to provide special safeguards. But, though less repulsive than other poisons, such substances are never positively attractive, and often (like verdigris, potassium, etc.), perceptibly nauseous. Vegetable poisons are either nauseous or intensely bitter. Hasheesh is more unattractive than turpentine. Opium is acrid caustic. Absinthe (wormwood extract) is as bitter as gall. Instinct resists the incipience of an insidious second nature. But that instinct is plastic. If the warnings of our physical conscience remain unheeded, if the offensive substance is again and again forced upon the unwilling stomach, nature at last chooses the alternative of compromising the evil, and, true to her supreme law, of preserving existence at any cost, prolongs even a wretched life by adapting the organism to the exigencies of an abnormal habit. She still continues her protest in the feeling of exhaustion which follows every poison-debauch, but permits each following dose of the insidious drug to act as a temporary re-invigorant, or at least as a spur to the functional activity of the exhausted organism, for the apparent return of vital vigor is, in fact, nothing but a symptom of the morbid energy exerted by the system in its efforts to rid itself of a deadly intruder, for each new application of the stimulus is as regularly followed by a distressing reaction. And _only then_ the slave of the unnatural habit becomes conscious of that peculiar craving which is entirely distinct from the promptings of a healthy appetite—a craving uncompromisingly directed toward a special—once repulsive—substance, a craving defying the limiting instincts which indicate the proper quantum of wholesome foods and drinks, a craving which each gratification makes more irresistible, though for the time being each indulgence is followed by a depressing reaction. The appetite for wholesome substances—however palatable—is never exclusive. A child may become passionately fond of ice cream, yet accept cold water and fruit cake as a welcome substitute. A predilection for honey, strawberries, or sweet tree fruits will not tempt the admirers of such dainties to commit forgery and highway robbery to indulge their penchant—as long as their kitchen affords a supply of savory vegetables. Unnatural appetites have no natural limits; but the art of the best pastry cook would hardly induce his customers to stupefy and bestialize themselves with his compounds. There are no milk topers, no suicidal potato eaters, no victims of a chronic porridge passion. In spite of