and separation, it was essential that the Church should proclaim and cherish. In Constantinople, a city always keen to debate theology in the streets, the divergence was plainly manifest; and a document which was "subtle to escape subtleties" was not likely to be satisfactory to the subtlest of controversialists. The Henotikon was accepted at Antioch, Jerusalem, and Alexandria, but it was rejected by Rome and by the real sense of Constantinople. In Alexandria the question was only laid for a time, and when a bishop who had been elected was refused recognition by Acacius the Patriarch of Constantinople and Peter "the Stammerer," who accepted the Henotikon, preferred to his place, a reference to Rome led to a peremptory letter from Pope Simplicius, to which Acacius paid no heed whatever. Felix II. (483-92), after an ineffectual embassy, actually declared Acacius excommunicate and deposed. The monastery of the Akoimetai at Constantinople ("sleepless ones," who kept up perpetual intercession) threw itself strongly on to the side of the advocates of Chalcedon. Acacius, then excommunicated by Rome because he would not excommunicate the Monophysite patriarch of Alexandria, retorted by striking out the name of Felix from the diptychs of the Church. {9} [Sidenote: Schism between East and West.] It was the first formal beginning of the schism which,--temporarily, and again and again, healed,--was ultimately to separate East and West; and it was due, as so many misfortunes of the Church have been, to the inevitable divergence between those who thought of theology first as statesmen and those who thought first as inquirers after the truth. The schism spread more widely. In Syria Monophysitism joined Nestorianism in the confusion of thought: in Egypt the Coptic Church arose which repudiated Chalcedon: Abyssinia and Southern India were to follow. Arianism had in the East practically died away; Nestorianism was powerful only in far-away lands, but Monophysitism was for a great part of the sixth century strong in the present, and close to the centre of Church life. The sixth century began, as the fifth had ended, in strife from which there seemed no outway. Nationalism, and the rival claims of Rome and Constantinople, complicated the issues. Under Anastasius, the convinced opponent of the Council of Chalcedon and himself to all intents a Monophysite in opinion, some slight negotiations were begun with Rome, while the streets of Constantinople ran with blood poured out by the hot advocates of theological dogma. In 515 legates from Pope Hormisdas visited Constantinople; in 516 the emperor sent envoys to Rome; in 517 Hormisdas replied, not only insisting on the condemnation of those who had opposed Chalcedon, but also claiming from the Caesar the obedience of a spiritual son; and in that same year Anastasius, "most sweet-tempered of emperors," died, rejecting the papal demands. {10}